Guinea pig cochlear blood flow was measured before and after systemic normovolemic hemodilution with high molecular weight dextran. Absolute determinations of blood flow (in the cochlea, brain, kidney and lung) were accomplished by use of radioactive-labeled (85Sr or 141Ce) microspheres. Relative measurements of the cochlear blood flow changes were made simultaneously by the use of a laser Dopp...

The red blood cell velocity and the arteriole-to-venule transit time of sodium fluorescein were measured in the pial microcirculation of 15 mice immediately before and after phlebotomy and hemodilution. The acute anemic state produced by die phlebotomy and hemodilution was accompanied by an increase in the velocity of the red blood cells and of the fluorescent plasma. Such increments in velocit...

Since the introduction of intravenous therapy, fluids containing glucose or saline in relatively isotonic concentrations have far exceeded others in use. Within the last decade new techniques in many areas of diagnosis and treatment have required that fluids of various tonicity and viscosity be introduced into the blood stream with such rapidity or in such great volume as to preclude adequate d...

Studies were made on the cellular components of the blood, the serum iron concentration, and the circulating blood and plasma volumes of rats in pregnancy and on the iron transport from the maternal blood to the conception products (uterus and its contents) using radioactive iron. Anemia of pregnancy developed and was most pronounced during late pregnancy when the conception products developed ...