BACKGROUND To describe the relationship between glycaemic control, hyperglycaemic symptoms and quality of life (HRQOL) in type 2 diabetic patients. METHODS In a shared-care diabetes project HRQOL was assessed. A total of 1664 patients with type 2 diabetes were identified in 32 primary healthcare practices. Of these patients, 1149 were included. HRQOL was measured using a generic questionnaire...

We outline a method for estimating either HbF or HbA content in single erythrocytes and their precursors. Our method depends on microphotometric assay of darkfield reflectance arising from individual pericellular immunoprecipitates developed with anti-HbF or anti-HbA. When uniform-diameter latex microspheres were used to normalize comparisons between preparations, mean coefficient of variation ...

OBJECTIVE The goal of this study was to describe medication usage patterns in patients with type 2 diabetes mellitus (T2DM) initiating treatment with non-insulin antidiabetic drugs (NIADs), basal insulin, or prandial/mixed insulin using real-world data. RESEARCH DESIGN AND METHODS A retrospective analysis using the Truven Health MarketScan Research Databases was conducted to identify adults (...

Introduction Glycated haemoglobin (HbA1c) is the best surrogate of average blood glucose control in diabetic patients, and lowering HbA1c significantly reduces diabetes complications. Moreover, immediate feedback of HbA1c measurement to patients may improve control. However, HbA1c is unavailable in most parts of Africa, a continent with one of the highest burden of diabetes. To translate these ...

BACKGROUND Body mass index (BMI) and hemoglobin (Hb) are positively associated with hypertensive disorders among pregnant women. The aim of this study was to estimate a potential interaction between high BMI and high Hb concentrations on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in pregnancy. METHODS We recruited 4497 single-birth women aged 18-43 years who received rou...

Glycosylated haemoglobin (HbA1c) is routinely used test to monitor long term glycaemic control in diabetic patients. It is well known that genetic variants and chemically modified derivatives of haemoglobin can profoundly affect the accuracy of HbA1c measurements. The degree of interference depends on the HbA1c assay method, type & quantum of haemoglobin variant present in a given sample. Here,...

The associations between psychosocial and physiological factors and diabetes' health indicators have not been widely investigated among Asians and Pacific Islanders. We hypothesize that health behaviour and depression are directly or indirectly associated with diabetes' health indicators such as BMI, glycemic control, general health, and diabetes quality of life. Our hypothesis was tested throu...

OBJECTIVE To investigate whether socioeconomic status and psychological well-being (eudaimonic and hedonic aspects) predicted nondiabetic levels of glycosylated hemoglobin (HbA1c) over time, after adjusting for covariates and baseline level of HbA1c. METHODS These questions were investigated with a longitudinal sample (n = 97; age = 61-91 years) of older women without diabetes. Socioeconomic ...

Using an HPLC procedure, we evaluated > 10 minor hemoglobins (Hbs) in healthy adults, individuals on long-term aspirin therapy, diabetic subjects, and uremic patients. Hb A1c and Hb A1d3 were the most abundant and important minor Hb components, respectively, accounting for 4.10% +/- 0.50% and 3.46% +/- 0.43% of total Hb in 361 healthy subjects. Acetylated Hb A was a potential interferent in the...

in a survey of 148 subjects (72 females and 76 males) in 3 villages and one city in isfahan province, plasma vitamin a, hemoglobin concentration and hematocrit were determined in all subjects, and serum iron was measured in 19 persons, in order to investigate the possible relationship between vitamin a and hematopoietic factors. a positive correlation existed between plasma vitamin a and hemogl...