Hemoglobin variant carrier status was found in a 46-year-old African American man following detection of a falsely elevated hemoglobin A1c (HbA1c) by ionexchange high-performance liquid chromatography (HPLC, VARIANT A1c, Bio-Rad Laboratories, Hercules, CA). Additional analysis of the hemoglobin variant using the Beta Thal Short program (Bio-Rad) revealed an unknown peak with a retention time of...

A total of 1,377 patients with symptomatic obstructive cerebrovascular disease (most commonly, internal carotid artery occlusion) entered a trial in which they were randomized to either medical or surgical (extracranial-intracranial bypass) therapy. All but 8 had hemoglobin estimations performed at entry. The patients were followed for an average of 55.8 months. In the medical group, the 325 pa...

Severe anemia is an important cause of morbidity and mortality among children in resource-poor settings, but laboratory diagnostics are often limited in these locations. To address this need, we developed a simple, inexpensive, and color-based point-of-care (POC) assay to detect severe anemia. The purpose of this study was to evaluate the accuracy of this novel POC assay to detect moderate and ...

We purified an extracellular hemoglobin with the molecular mass of ca. 440 kDa from the whole homogenates of Oligobrachia mashikoi (phylum Pogonophora) by a one-step gel-filtration. The preparation was pure to be crystallized. The P50 values of the hemoglobin and the fresh blood prepared from O. mashikoi were about 0.82 Torr and 0.9 Torr, respectively, which were much lower than the P50 value o...

Objectives. We aimed to examine whether baseline hemoglobin levels in C282Y-homozygous patients are related to the degree of serum ferritin (SF) elevation and whether patients with different baseline hemoglobin have different phlebotomy requirements. Methods. A total of 196 patients (124 males and 72 females) who had undergone therapeutic phlebotomy and had SF and both pre- and posttreatment he...

=> 7' 7 ,72 Recent studies of chronic hypercapnia in guinea pigs and rats demonstrated a biphasic shift in the blood oxygen dissociation curve, a diminution of heme-heme interaction and a significant decrease in the oxygen capacity of blood which was not due to decreased hemoglobin content. The latter finding suggested production of non-functional hemoglobin during hypercapnia. We measured the ...

Artificial oxygen carriers (AOCs) can be abused by the athletes to improve their aerobic capacity. The AOCs produce a performance enhancing effect, especially in endurance sports. This article presents a method for the rapid screening of hemoglobin-based oxygen carriers (HBOCs) in blood samples. Common screening tests to reveal HBOC misuse by athletes are based on colorimetric detection since H...

  Background: Routine repeat testing of critical laboratory values is very common these days to increase their accuracy and to avoid reporting false or infeasible results. We figure that repeat testing of critical laboratory values has any benefits or not.   Methods : We examined 2233 repeated critical laboratory values in 13 different hematology and chemistry tests including: hemoglobin, white...

Aim: Abnormal uterine bleeding is a common condition. The etiological cause and treatments are diverse. LNG-IUD can be used to treat abnormal bleeding.It has been shown reduce the amount of in patients with menorrhagia increase hemoglobin hematocrit (Hct) values. aim investigate effects on hemoglobin, Hct, pattern, its effect sexual function, decision regret, according etiologic cause.
 Ma...

SUMMARY OBJECTIVE: Serum inflammatory markers and albumin levels provide an assumption for the severity of COVID-19 infection. Our objective was to investigate determinant role serum markers, albumin, hemoglobin (Hb) in predicting diagnosis patients with a pre-diagnosis COVID-19. METHODS: Demographic findings, complete blood count biochemical values analyzed. RESULTS: Of included study, 48 were...