Abstract Superficial Siderosis of the Central Nervous System (SSCNS) is a condition secondary to deposition hemosiderin within subpial layers central nervous system leading its progressive degeneration, clinically responsible for hearing impairment, cerebellar ataxia and pyramidal syndrome. Here we report case 61-year-old man with medical history congenital hemophilia A presenting typical clini...

Pseudomelanosis is a rare endoscopic finding of the upper gastrointestinal tract characterized by hemosiderin deposits in histiocytes of lamina propria. We report a case of 72-year-old lady on chronic oral iron supplementation diagnosed with gastric hyperplastic polyps with background pseudomelanosis of stomach and duodenum. Concomitant occurrence of gastric pseudomelanosis, duodenal pseudomela...

A 50-year-old Taiwanese woman had a history of massive hemoptysis occurring every 6 months for the past 4 years. After each bout of hemoptysis, chest roentgenography would show diffuse alveolar infiltration of bilateral lungs, which would usually resolve within 7 days. Transbronchial biopsy revealed diffuse alveolar hemorrhage and hemosiderin-laden macrophage infiltration. Idiopathic pulmonary ...

We herein report a 73-year-old Japanese woman with metastatic thymic carcinoma who developed diffuse alveolar hemorrhage (DAH) during irinotecan chemotherapy. She presented with a mild fever and exertional dyspnea after the second cycle of weekly irinotecan monotherapy. Chest images showed diffuse ground-glass opacities. The diagnosis of DAH was based on the findings of the bronchoalveolar lava...

Recently, there has been an interest in using an argon laser to initiate polymerization of light-activated materials [11]. The argon laser, the active medium of which is argon gas, produces light at two wavelengths. The 488 nm blue light is commonly used to initiate the polymerization of restorative composite materials. The 514 nm blue green light has maximum absorbance in tissues that are comp...

H EMOCHROMATOSIS was first described by Hartman and Chausser in i88i as “bronze diabetes” because of the association of skin pigmentation with diabetes mellitus. Von Recklinghausen in 1889 showed that the pigmentation of the skin and viscera was due to deposits of hemosiderin and hemofuscin. Hemochromatosis was considered quite rare, being clinically diagnosed only three times in i6o,ooo admiss...

I N PREVIOUS PUBLICATIONS, we have shown that a part of the iron cycle may be studied by means of the electron microscope.’3 Actually, in the bone marrow of both humans and marnmifers the reticulum cells may be observed in the process of digesting the aged cells. Digestion continues for approximately 5 to 15 minutes as revealed by microcinematography by which the red cells may be seen immediate...

Brown tumors are giant cell focal lesion that arises as a result of abnormal bone metabolism in patients with hyperparathyroidism (HPT). The lesions localize in areas of extensive bone resorption, which is replaced by fibrovascular tissue and giant cells with abundant deposits hemorrhage and hemosiderin. A rare case of brown tumor of mandible in a 22-year-old woman is reported here. This case e...

Cholesterol granulomas are composed of a distinct type of granulation tissue that contains lipids and cholesterol crystals. They are not believed to be a pathological entity, but rather an inflammatory tissue reaction to the presence of trapped blood secondary to localized hemorrhage.1 Cholesterol granulomas can be identified histologically by the presence of multi-nucleated giant cells, hemosi...