The structure of bacteriorhodopsin based on electron microscopy (EM) studies, as provided in Henderson et al. (1990), is refined using molecular dynamics simulations. The work is based on a previously refined and simulated structure which had added the interhelical loops to the EM model of bR. The present study applies an all-atom description to this structure and constraints to the original He...

In just over half a century plastic products have revolutionized human society and have infiltrated terrestrial and marine environments in every corner of the globe. The hazard plastic debris poses to biodiversity is well established, but mitigation and planning are often hampered by a lack of quantitative data on accumulation patterns. Here we document the amount of debris and rate of accumula...

1. Olds D, Henderson CR, Cole R, et al. Long-term effects of nurse home visitation on children’s criminal and antisocial behavior: 15-year follow-up of a randomized controlled trial. JAMA. 1998;280:1238-1244. 2. The Infant Health Development Program. Enhancing the outcomes of low birth weight, premature infants: a multisite, randomized trial. JAMA. 1990;263:3035-3042. 3. Brooks-Gunn J, McCarton...

When individual titratable sites in a molecule interact with each other, their pH titration can be considerably more complex than that of an independent site described by the classical Henderson-Hasselbalch equation. We propose a novel framework that decomposes any complex titration behavior into simple standard components. The approach maps the set of N interacting sites in the molecule onto a...

Left ventricular systolic and diastolic function improve after acute myocardial infarction treated with acute percutaneous coronary intervention, but are not influenced by intracoronary injection of autologous mononuclear bone marrow cells: a 3 year serial echocardiographic substudy of the randomized-controlled ASTAMI study. Eur J Echocardiogr 2011;12:98–106. [9] Henderson NC, Mackinnon AC, Far...

This case report presents a 49 year-old female with type 1 diabetes admitted to the intensive care unit with acute respiratory failure and severe diabetic ketoacidosis with an initial measurement of blood glucose level of 1,200 mg L⁻¹, pH 6.78, serum HCO₃ ⁻ 3.2 mmoL L⁻¹ and BE -31.2 mmoL L⁻¹. Analysis of the blood gasometric parameters with the Stewart approach and the traditional Henderson-Has...

The fact that trade protection hurts the economy of the country that imposes it is one of the oldest but still most startling insights economics has to offer. The idea dates back to the origin of economic science itself. Adam Smith's The Wealth of Nations, which gave birth to economics, already contained the argument for free trade: by specializing in production instead of producing everything,...

Through C. R. Henderson's position and the application of his knowledge, he had a major influence on genetic improvement in dairy cattle beginning in the 1950s. He developed herdmate comparisons in the United States. The first extensive program using pedigree selection and progeny testing of sires for use in AI was because of his suggestion. This program established the direction of dairy cattl...

We tested the hypothesis that fixation locations during scene viewing are primarily determined by visual salience. Eye movements were collected from participants who viewed photographs of real-world scenes during an active search task. Visual salience as determined by a popular computational model did not predict region-to-region saccades or saccade sequences any better than did a random model....