1. The effects of restricted feeding, and ad lib. feeding following food restriction, on hepatic carbohydrate and lipid metabolism in the laying hen were studied. 2. The birds were allocated to four groups and given either 92, 84 or 75 g/d or allowed ad lib. access to food. 3. Food restriction significantly reduced liver total lipid content compared with ad lib.-fed control birds and this was r...

Microsomal and cytosolic enzymes that metabolize xenobiotics were measured in composite samples representing entire livers and in samples from three lobes, using livers of cattle, goats and sheep. Within individual species, concentrations of cytochrome P-450 and b s and activities of NADPH cytochrome c reductase, aldrin epoxidase, aminopyrine N-demethylase, ethoxycoumarin O-deethylase, microsom...

Objective(s): Liver transplantation is the most important therapy for end-stage liver disease and ischemia reperfusion (I/R) injury is indeed a risk factor for hepatic failure after grafting. The role of miRNAs in I/R is not completely understood. The aim of this study was to investigate the potential protective role of the mesenchymal stem cells (MSCs) and ischemic pr...

Lipogenic capacity of various dietary carbohydrates starch, glucose sucrose and lactose was tested during ad lib feeding and starvation followed by refeeding. Sucrose was found to have maximal effect on hepatic total lipid and the enzymes in the study followed by glucose and sago while lactose was found to be toxic. Starvation resulted depression in the activities of various enzymes. The enzyme...

The capacity of the testis to metabolize xenobiotics has been proposed to play a role in the susceptibility of different species to testicular toxicity. Since species differences in testicular xenobiotic metabolizing enzyme activities are not well documented, the primary objective of the present study was to compare enzyme activities in subcellular fractions prepared from rat, mouse, monkey, an...

Microsomal and cytosolic enzymes that metabolize xenobiotics were measured in composite samples representing entire livers and in samples from three lobes, using livers of cattle, goats and sheep. Within individual species, concentrations of cytochrome P-450 and b5 and activities of NADPH cytochrome c reductase, aldrin epoxidase, aminopyrine N-demethylase, ethoxycoumarin O-deethylase, microsoma...

Sulphate ions have been known for some years to enhance the activity of hepatic glycogen phosphorylase b in vitro. Here we report that intravenous injections of 4.92 mmol of Na2SO4/kg body wt. to rats induced marked hepatic glycogenolysis in vivo, accompanied by polyuria, glycosuria and a mild hyperglycaemia. These effects were observed both in normal (Wistar) rats and in gsd/gsd rats that lack...

Ethanol exerts its pbarmacologlcal effects by alteriag the pkysico-ckemical propeof biological membranes. Modlflcatlons induced by ethanol may reta& in ckangeg lo the activity of membtane-boand enzymes tkat have been shown to reqdre a speclflc membram? flnldlty and composition for optimal function. In tbll study we have carried oat the analysis of the effects of ethanol on the different enzyme ...

ACAC), and fatty acid synthetase (FAS) were studied in male Wistar rats after a period of starvation and refeeding of diets containing 400 g glucose, or raw or cooked starches as the source of carbohydrate/kg. Starches fed included maize, potato, wheat, rice, and tapioca. 2. When compared to the responses of rats given the glucose-containing diet, rats given raw maize-or rice-starch-containing ...