نتایج جستجو برای: hepatitis b immune epitopes
تعداد نتایج: 1188089 فیلتر نتایج به سال:
Background: Hepatitis B vaccination has been included in routine immunization of all individuals according to WHO recommendations since 1991. Despite successful coverage, 3-5% of recipients fail to mount a desirable protection level of Ab. Vaccine failure results from: emergence of mutation, immune failure of individuals, decrease in vaccine potency, and etc. The quality of Hepatitis B va...
HIV-infected children had a lower seroconversion rate to hepatitis B immunization and a more rapid antibody decline when compared to healthy children. Whether re-immunization or additional booster dose is necessary after immune recovery remains unknown. This study was conducted to determine the prevalence of hepatitis B virus protective antibody in HIV-infected children with immune recovery aft...
hepatitis b virus (hbv) is the most prevalent viral infection and is among the leading causes of human liver diseases. nearly 360 millions of people are world widely infected with prolonged forms of hepatitis b including active and inactive chronic forms. chronic hepatitis b (chb) is associated with cirrhosis and hepatocellular carcinoma (hcc) in patients suffering from congenital and/or acquir...
We have previously demonstrated that the murine humoral immune responses to the group-specific a and subtype-specific d/y determinants of hepatitis B surface antigen (HBsAg) are controlled by H-2-linked immune response (Ir) genes. High responder (H-2d,q), intermediate responder (H-2a greater than b greater than k) and nonresponder (H-2f,s) haplotypes have been identified (8, 9). The kinetics an...
BACKGROUND & AIMS Impaired T-cell reactivity is believed to be the dominant cause of chronic hepatitis B virus (HBV) infection. We characterized HBV-specific T-cell responses in chronic hepatitis B surface antigen carriers who received bone marrow from HLA-identical donors with natural immunity to HBV and seroconverted to antibody to hepatitis B surface antigen. METHODS T-cell reactivity to H...
<b><i>Background:</i></b> Chronicity or seroclearance of hepatitis B virus (HBV) antigens is determined by the host immune responses. Current approaches to treat HBV patients are based on inhibition replication using different antivirals (nucleoside nucleotide analogs) as monotherapy, along with modulators combination therapy being used worldwide for reducing viral load....
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