We successfully re-vaccinated hepatitis B virus (HBV) vaccine non-responders using a double dose of the combined hepatitis A virus (HAV) and HBV vaccine. The hope was to improve priming of hepatitis B surface antigen (HBsAg)-specific cell mediated immune response (CMI) by an increased antigen dose and a theoretical adjuvant-effect from the local presence of a HAV-specific CMI. A few non-respond...

abstract        background and objective: aluminum salts are among the most common useful additive compounds in preparation of human and animal vaccines. aluminum phosphate and aluminum hydroxide are two additives that show good immunoadjuvant effects with many antigens. aluminum-containing vaccines lead to a better and longer immune response compared to adjuvant-lacking vaccines. the chromogen...

(1) All HIV-positive patients should have serum markers for hepatitis B checked (HBsAg, anti-HBc and/or antiHBs) tests within a month of diagnosis [II]. (2) All those negative for hepatitis B markers should be immunized and anti-HBs checked at 12 weeks. Patients failing to respond to a conventional course of 20 mg vaccine should received booster doses and/or a repeat vaccination cycle with the ...

Background: Poor response to various vaccines especially hepatitis B is common. The purpose of this study was to evaluate the effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients. Methods: In this randomized clinical trial study, 62 insulin dependent diabetic patients were divided into case and control groups (...

Hepatitis B virus (HBV) is a serious global health problem. The development of a safe and effective vaccinewould help infection prevention. Previous hepatitis B vaccine production involved the isolation of the noninfectious particle from chronic HBV carriers. DNA recombinant technology has been used for vaccineproduction without having been contaminated with blood-born infectious ag...

hepatitis b vaccination coverage among teaching hospitals workers in the urmia city ali gholami, tahereh alinia , leila moosavi jahromi * received: 25 april, 2010 accepted: 27 july, 2010 abstract introduction: hepatitis b virus infection is a well recognized risk for healthcare workers (hcws). for protect hcws of hepatitis b, vaccination has been recommended. the aim of this study is survey of...

We read with great interest the article, “efficacy of hepatitis B vaccine in those who lost hepatitis B surface antigen during follow-up” by Taheri et al. published in Hepatitis Monthly (1). In this article, the authors assessed the efficacy of HBV vaccine in those who lost their HBsAg without seroconverssion to anti-HBs antibody with no detectable anti-HBs antibody and HBV DNA in their sera. T...

In this cross sectional anonymous study, blood samples of 285 dentists and Physicians were tested for hepatitis B surface antigen (HBs Ag), hepatitis B envelope Ag (HBe Ag), antibodies to: hepatitis B suface (anti-HBs), hepatitis B core Ag (anti-HBc) and hepatitis B envelope Ag (anti-HBe) by ELISA-3 and antibody to hepatitis C virus (anti-HCV) by ELISA-3 and immunoblotting tests. The results su...

The anti-pre-S antibody in the samples of sera from normal healthy persons and patients with different clinical types of liver diseases due to hepatitis B virus (HBV) infection was detected by a newly established enzyme-linked immunosorbent assay technique. This test is a blocking assay where anti-pre-S antibody in the patient's serum blocks subsequent addition of horse radish peroxidase-labell...