Sir, Interferons (IFNs) are cytokines widely used in medicine for their antiproliferative, antiviral and immunomodulatory effects. Their most common side effect is an in ̄uenza-like syndrome characterized by fever, headache and muscle pain. Also, IFNs infrequently induce or worsen some dermatoses, such as herpes labialis, psoriasis, pemphigus and vitiligo (1). Several papers have referred to the...

Cold sores are caused by a herpes virus, most often the herpes simplex 1 virus. Cold sores should not be confused with canker sores, which are small ulcerations in the mouth. Rather, cold sores are fluid-filled blisters that form on the gums and the outside of the mouth and lips. The blisters, which are contagious, later break, ooze, and crust over before healing. Recurrences are common and can...

There are two main competing hypotheses (vicariance and vertical ecotones) that attempt to explain the tremendous diversity of the tropical Andes. We test these hypotheses at the intraspecific level by analyzing mitochondrial and nuclear DNA sequences from 24 populations of the high Andean frog, Dendropsophus labialis (Anura: Hylidae). This species displays geographic variation in a number of p...

The Asian pitviper currently identified as Trimeresurus labialis Fitzinger in Steindachner, 1867 is revised on the basis of morphological data obtained from 37 preserved specimens originating from seven islands of the Nicobar Islands. Multivariate analyses shows that these specimens can be divided into two clusters of populations which differ by a series of constant taxonomically informative mo...

Complex interactions between topographic heterogeneity, climatic and environmental gradients, and thermal niche conservatism are commonly assumed to indicate the degree of biotic diversification in montane regions. Our aim was to investigate factors that disrupt gene flow between populations and to determine if there is evidence of downslope asymmetric migration in highland frogs with wide elev...

Changes in the hardness, dissolution, and the disintegration time of brand name and generic preparations (6 preparations) of famotidine orally disintegrating tablets were investigated. Tablets had been stored in a thermo-hygrostat-controlled environment set to simulate the home conditions of patients up to 8 weeks after unit-dose packaging. Among the tablets in unit-dose packaging prepared imme...

OBJECTIVE The aims of the present study were to examine the Zn intake and characteristics of Zn supplement users and non-users and to survey Zn supplements that are commercially available. DESIGN Cross-sectional national nutrition survey (2007 Australian Children's Nutrition and Physical Activity Survey) and a review of commercially available Zn supplements. SETTING Australia. SUBJECTS Ch...

The high work-related loads on the skin of dancers is result numerous factors. While initial studies have looked at consequences exposure, information condition still completely lacking. This study includes for first time an analysis as well relevant care behaviour. Methods: A total n = 35 professional (PT) underwent (transepidermal water loss, TEWL; moisture content and oil level) part a derma...