The present paper explore out the better-characterized and most intensively studied oncogenic viruses of humans and animals. Many DNA and RNA viruses have been proved to be oncogenic (or carcinogenic) in a variety of animals, ranging from amphibia to primates, and évidence grows stronger that certain forms of human cancer are of viral origin. Several DNA viruses have been associated with the ca...

In a search for past or present infection with herpes viruses, serum antibody titres to herpes simplex type 1 virus, cytomegalovirus, and varicella-zoster virus were measured by complement fixation test in 58 patients with achalasia. Serum was also taken from 40 age and sex matched patients without oesophageal symptoms who formed a control group. All titres were low, and those for herpes simple...

Encephalitis is an acute infl ammation of the meninges and cerebral tissue. Although the specifi c etiological agent is not identifi ed in many instances, clinical and research experience indicate that viruses are the responsible pathogens for most infections. Enteroviruses cause more than 80% of all cases (1, 2). The other frequent viral causes are arboviruses and Herpes viruses. Herpes simple...

Benzalkonium chloride (as Roccal or Zephiran) was found to inactivate influenza, measles, canine distemper, rabies, fowl laryngotracheitis, vaccinia, Semliki Forest, feline pneumonitis, meningopneumonitis, and herpes simplex viruses after 10 min of exposure at 30 C or at room temperature. Poliovirus and encephalomyocarditis virus were not inactivated under the same conditions. It was concluded ...

Latent infections with periodic reactivation are a common outcome after acute infection with many viruses. The latency-associated transcript (LAT) gene is required for wild-type reactivation of herpes simplex virus (HSV). However, the underlying mechanisms remain unclear. In rabbit trigeminal ganglia, extensive apoptosis occurred with LAT(-) virus but not with LAT(+) viruses. In addition, a pla...

A strain of camel kidney cells was developed and carried in serial passages. The subcultures were slow-growing in the early passages and were composed of heterogeneous cell population. By the 35th passage, the growth rate increased, and more homogeneous cells, mostly of the epithelioid type, were seen. The cell strain was highly susceptible to West Nile, Sindbis, vesicular stomatitis, adeno, an...

Epigallocatechin gallate (EGCG) (Figure 1a) is the major catechin component of green tea (Camellia sinensis). It has been shown to have antiviral properties against DNA viruses such as herpes simplex virus (HSV; Herpesviridae) [1], adenovirus (Adenoviridae) [2], human papilloma virus (HPV; Papovaviridae) [3], and hepatitis B virus (HBV; Hepadnaviridae) [4], and RNA viruses such as influenza vir...

Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA viruses. However, such machinery is well characterized in tailed bacteriophage, which share a common evolutionary origin with herpesvirus. In tailed...

Objective(s) The aim of this study was to search for new antiviral agents from herbal medicines. Ethanol extracts of C. semipervirens, C. semipervirens var. horizontalis and C. semipervirens cv. Cereiformis were used in experiments to test their influence on herpes viruses (HSV-1). Materials and Methods HeLa cells monolayers were infected with herpes viruses (HSV-1). Antiviral activity of the p...

Thermal destruction rate curves were determined for adenovirus 12, reovirus 1, and herpes simplex virus in sterile milk, raw milk, raw chocolate milk, and raw ice cream mix. At 40 to 60 C, the curves were asymptotic to the base line. At 65 C, which is near the pasteurization standard, the curves approached a first-order reaction. Thermal resistance studies, by means of in vivo assays, of Molone...