~ Departrnent of Virology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565, 2 Department of Pathology, National Institute of Health, Tokyo, 3Department of Animal Pathology, Institute of Medical Science, University of Tokyo, Tokyo, 4Research Center for Immunodeficiency Virus, Institute for Virus Research, Kyoto University, Kyoto, Japan, 5Faculty of S...

into 2 classes. One has to do with experimental design and the total maximum amount of DNA in a system. Our reaction mixture contained a maximum concentration of DNA of approximately 5 mg/ml, in a volume of the order of 25 to 50 /¿I. Second, we had deliberately chosen not to plot the data according to C0t because we believe our method of data presentation to be far more sensitive. Dr. Roizman ...

This paper critically assesses the design implications for the analysis of surveys of infections. It indicates the danger of not accounting for the study design in the statistical investigation of risk factors. A stratified design often implies an increased precision while clustering of infection results in a decreased precision. Through pseudo-likelihood estimation and linearisation of the var...

Species within the Neoromicia bat genus are abundant and widely distributed in Africa. It is common for these insectivorous bats to roost in anthropogenic structures in urban regions. Additionally, Neoromicia capensis have previously been identified as potential hosts for Middle East respiratory syndrome (MERS)-related coronaviruses. This study aimed to ascertain the gastrointestinal virome of ...

UNLABELLED Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae, and is a recently discovered emerging herpesvirus that is highly pathogenic for koi and common carp. Our previous study demonstrated that CyHV-3 becomes latent in peripheral white blood cells (WBC). In this study, CyHV-3 latency was further investigated in IgM(+) WBC. The p...

UNLABELLED Membrane fusion is indispensable for entry of enveloped viruses into host cells. The conserved core fusion machinery of the Herpesviridae consists of glycoprotein B (gB) and the gH/gL complex. Recently, crystal structures of gH/gL of herpes simplex virus 2 (HSV-2) and Epstein-Barr virus and of a core fragment of pseudorabies virus (PrV) gH identified four structurally conserved gH do...