The family Herpesviridae is a large, diverse family of double-stranded enveloped DNA viruses. Herpes B virus (BV) and Cercopithecine herpesvirus 2 (CeHV-2) are simian herpesvi-ruses. Like herpes simplex virus 1 (HSV-1), they belong to the a-herpesvirus subfamily. interest in BV infections results from the observation that zoonotic infections often result in death of humans, whereas infection of...

Photodynamic inactivation of virus was tested as a potential therapeutic tool for herpesvirus-induced keratitis, which is a leading cause of blindness and disability. Experimental keratitis produced in rabbits by infection with herpesvirus isolated from a human periorbital lesion was treated with proflavine and light. The herpetic keratitis could be rapidly resolved by the dye-light treatment, ...

The disease is caused by members of the gammaherpesviruses group. Alcelaphine herpesvirus-1 (AHV-1), carried asymptomatically by the wildebeest (Connochaetes taurinus) in Africa, has been diagnosed in disease outbreaks in zoos in North America. Ovine herpesvirus-2 (OHV-2) is carried asymptomatically by sheep (117). A third, as yet unnamed virus, has been detected in an outbreak of MCF in white-...

Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus belonging to the gamma-herpesvirinae subfamily. KSHV has been associated with the development of three neoplastic diseases: Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). In this review, we discuss the three KSHV-associated malignancies, KSHV genome, latent and lyti...

experience with herpesvirus type 2 than with the presence or absence of cervical cancer. Thymidine kinase extracted from cervical cancer cells was found to migrate on polyacrylamide gel electrophoresis in a pattern similar to those of the enzymes induced in cells by herpesvirus types 1 or 2. The enzyme of the cancer tissue, however, did not appear to be antigenically related to the virus-induce...

Citation: Simanek AM, Uddin M, Yolken RH and Aiello AE (2016) Use of Archived Neonatal Bloodspots for Examining Associations between Prenatal Exposure to Potentially Traumatic or Stressful Life Events, Maternal Herpesvirus Infection and Lifetime History of Generalized Anxiety Disorder in Offspring. Front. Environ. Sci. 4:54. doi: 10.3389/fenvs.2016.00054 Use of Archived Neonatal Bloodspots for ...

In this paper we discuss the use of Herpesvirus saimiri as a model for the development of vaccines against herpesvirus-induced neoplasia in primates. Attempts at protection against the oncogenicity of H. saimiri have centered on the inactivation of virus by heat and formalin, the production of temperature-sensitive H. saimiri mutants, and the attenuation of the virus. Each of these approaches h...

RF: HHV-8 and multiple myeloma in the UK. Lancet 350:1144, 1997 (letter) 7. Gao S-J, Alsina M, Deng J-H, Harrison CR, Montalvo EA, Leach CT, Roodman GD, Jenson HB: Antibodies to Kaposi’s sarcomaassociated herpesvirus (human herpesvirus 8) in patients with multiple myeloma. J Infect Dis 178:846, 1998 8. Basten A, Brink R, Peake P, Adams E, Crosbie J, Hartley S, Goodnow CC: Self tolerance in the ...

Classical herpesvirus particles were observed by thin-section electron microscopy in thymus tissues from mice inoculated with mouse thymic virus. Intranuclear particles measured approximately 100 nm in diameter, and cytoplasmic and extracellular particles measured 135 nm in diameter. The morphology of mouse thymic virus particles together with its properties of heat and ether lability suggest t...

RF: HHV-8 and multiple myeloma in the UK. Lancet 350:1144, 1997 (letter) 7. Gao S-J, Alsina M, Deng J-H, Harrison CR, Montalvo EA, Leach CT, Roodman GD, Jenson HB: Antibodies to Kaposi’s sarcomaassociated herpesvirus (human herpesvirus 8) in patients with multiple myeloma. J Infect Dis 178:846, 1998 8. Basten A, Brink R, Peake P, Adams E, Crosbie J, Hartley S, Goodnow CC: Self tolerance in the ...