Inhibitory activity of thirty-one ethanol extracts obtained from albedo, flavedo, seed and leaf parts of 17 cultivars of Citrus species from Turkey, the bark and leaves of Olea europaea L. from two locations (Turkey and Cyprus) as well as caffeic acid and hesperidin was tested against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), related to the pathogenesis of Alzheimer's diseas...

We evaluated the effects of Rikkunshi-to and several of its ingredients on the delay of gastric emptying induced by a nitric oxide (NO) synthase inhibitor, N(G)-nitro-L-arginine (L-NNA). After oral administration of L-NNA to rats, the gastric emptying rate at 24 h was decreased from 82.8 +/- 2.4% to 53.3 +/- 5.7%. The decrease of the gastric emptying rate induced by L-NNA treatment was markedly...

In this study combination of diosmin and hesperidin was used for the treatment a condition called chronic venous insufficiency. are citrus bioflavonoids that act as vascular-protecting agents to treat insufficiency, hemorrhoids, lymphedema, varicose veins. A preformulation carried out formulation tablet selected drug. compatibility between along with excipients like

Sickle cell disease (SCD) is still one of the highest leading inbred hemoglobinopathy amid Africans. The In-vitro effects hesperidin on sickling human erythrocytes with functional chemistry sickle were investigated by standard methods.The induction in was done using 2%sodium metabisulphite at 3 hours optimally. prevention and curative approaches (PA CA) adopted comparison erythrocytesfrom AA-ge...

Different ensemble strategies were compared in online near-infrared models for monitoring active pharmaceutical ingredients of Traditional Chinese Medicine. Bagging partial least square regression and boosting partial least square regression were adopted to near-infrared models, to determine hesperidin and nobiletin content during the extraction process of Pericarpium Citri Reticulatae in a pil...

Model performance of the partial least squares method (PLS) alone and bagging-PLS was investigated in online near-infrared (NIR) sensor monitoring of pilot-scale extraction process in Fructus aurantii. High-performance liquid chromatography (HPLC) was used as a reference method to identify the active pharmaceutical ingredients: naringin, hesperidin and neohesperidin. Several preprocessing metho...

The aim of this study was to investigate the protective effects of juice powders from sweet orange [Citrus sinensis (L.) Osbeck], unshiu mikan (Citrus unshiu Marcow), and mini tomato (Solanum lycopersicum L.), and their major flavonoids, hesperidin, narirutin, and rutin in tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in HepG2 cells. The increased reactive oxygen species and decreas...

Among the large number of plants that are part Ayurvedic system medicine in India and Bangladesh, Zingiber officinale Roscoe (Zingiberaceae), or ginger English, holds a special place is often referred to as “Mahaushadha” (great medicine) “Vishvabhesaja” (worldwide universal herb) signify its status. The plant particularly rhizomes used both raw dry form for relief multitude disorders. Since the...