Real-time PCR continues to have a major impact across many disciplines of the biological sciences and this has been a driver to develop and improve existing instruments. From the first two commercial platforms introduced in the mid 1990s, there is now a choice in excess of a dozen instruments, which continues to increase. Advances include faster thermocycling times, higher throughput, flexibili...

Hidekazu Taoka and Kenichi Higuchi An ultra-high-speed packet transmission experiment for achieving a transmission data rate of approximately 5 Gbit/s (spectral efficiency of 50 bit/s/Hz) was performed using a 100-MHz channel bandwidth in broadband packet radio access. The spectrum efficiency of 50 bit/s/Hz nearly approaches the upper limit in cellular environments near a cell site taking into ...

Sustained release tablets of Rosuvastatin were developed to prolong r e l e a s e o f time leading to an increase in drug bioavailability.Tablets are prepared by direct compression technique using polymers HPMC K15M,HPMC K50M and ethylcellulose.Tablets were evaluated for their physical characteristics viz.,hardness, thickness, friability and weight variation, drug content and floating propertie...

Matthew J. McGirt, Augusto Parra, Huaxin Sheng, Yoshinori Higuchi, Tim D. Oury, Daniel T. Overexpressing Extracellular Superoxide Dismutase Attenuation of Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Aven...

*Correspondence: [email protected] 1Nalecz Institute of Biocybernetics and Biomedical Engineering PAS, Warsaw, Poland Full list of author information is available at the end of the article Abstract Background: The chess game is a good example of cognitive task which needs a lot of training and experience. The aim of this work is to compare applicability of two nonlinear methods Higuchi Fract...

Since the invention of real-time PCR (qPCR), thousands of high-impact studies have been conducted and published using qPCR technique (Heid et al. 1996; Higuchi et al. 1993; VanGuilder, Vrana, and Freeman 2008). Because it is highly sensitive, qPCR is the preferred method for microarray data validation (Canales et al. 2006); however the most exciting applications have been in the discovery of ne...

One of the most well-known classical results for site percolation on the square lattice is the equation pc + p ∗ c = 1. In words, this equation means that for all values 6= pc of the parameter p the following holds: Either a.s. there is an infinite open cluster or a.s. there is an infinite closed ‘star’ cluster. This result is closely related to the percolation transition being sharp: Below pc ...

One of the most well-known classical results for site percolation on the square lattice is the equation pc +p∗ c = 1. In words, this equation means that for all values = pc of the parameter p, the following holds: either a.s. there is an infinite open cluster or a.s. there is an infinite closed “star” cluster. This result is closely related to the percolation transition being sharp: below pc, t...

BACKGROUND AND THE PURPOSE OF THE STUDY Lercanidipine hydrochloride (LRDP) is used in the treatment of hypertension because of its selectivity and specificity on the smooth vascular cells. The pharmacokinetic parameters make LRDP a suitable candidate for transdermal delivery. The purpose of the study was to select a suitable formulation for the development of transdermal drug-delivery system (T...

The purpose of this study was formulation and in vitro evaluation of floating-bioadhesive tablets to lengthen the stay of glipizide in its absorption area. Effervescent tablets were made using chitosan (CH), hydroxypropyl methylcellulose (HPMC), carbopolP934 (CP), polymethacrylic acid (PMA), citric acid, and sodium bicarbonate. Tablets with 5% effervescent base had longer lag time than 10%. The...