Evolutionary approaches to cultural change are increasingly influential, and many scientists believe that a 'grand synthesis' is now in sight. The papers in this Theme Issue, which derives from a symposium held by the AHRC Centre for the Evolution of Cultural Diversity (University College London) in December 2008, focus on how the phylogenetic tree-building and network-based techniques used to ...

Central serous chorioretinopathy (CSCR) is an idiopathic ocular condition - first described in 1866 - that is well known to ophthalmologists. It is less well known to other practitioners. Glucocorticoids have been strongly implicated as a pathogenic factor. We report three patients who developed CSCR following exogenous administration of corticosteroid. Because our patients did not suspect the ...

There have been relatively few attempts to represent sight or blindness ontologically. This is unsurprising as the related phenomena of sight and blindness are surprisingly difficult to represent ontologically for a variety of reasons. This paper discusses those reasons, explores the current attempts to represent sight or blindness, and how these attempts fail at representing certain types of b...

Among the challenging issues that affect the performance of wireless location techniques is the temporal and spatial variations of the channel, and the distribution of the scatterers, which introduce non-line-of sight errors at the base station. This paper develops a technique for addressing this problem by exploiting the topology of the cellular network.

Two-way time of flight (ToF) ranging is one of the most interesting approaches for localization in wireless sensor networking since previous ToF ranging approaches using commercial off-the-shelf (COTS) devices have achieved good accuracy. The COTS-based approaches were, however, evaluated only in line-of-sight conditions. In this paper, we extend ToF ranging using multiple IEEE 802.15.4 channel...

We consider the problem of reconstructing the location of a moving 3D point seen from a monocular moving camera, i.e., to reconstruct moving objects from line-of-sight measurements only. Since the point is moving while the camera is moving, then even if the camera motion is known, it is impossible to reconstruct the 3D location of the point under general circumstances. However, we show that if ...

174 The invention of freeze fracture EM and the determination of membrane structure Catching sight of lysosomes ll we wanted was to know something about the localization of glucose-6phosphatase, which we thought might provide a possible clue to the mechanism of action, or lack of action, of insulin on the liver cell.” Thus begins Christian de Duve’s discovery of lysosomes, which he first visual...

Starting its work ahead of the Brazilian Society of Dermatoloy, the new editorial board intends to implement some changes aiming mainly at improving the quality of the journal. A decision considered crucial is the standardization of the print magazine exclusively in Portuguese, since this version is directed primarily to domestic readers. Thus, the national authors and foreigners who have Portu...