His-Asp phosphorylation pathways (also known as two-component systems) enable bacteria (and primitive eukaryotic cells and/or eukaryotic organelles) to make important adaptive decisions in response to fluctuations in intraor extracellular chemical and/or physical conditions. These sensory systems are composed of a dimeric sensor protein, with an input domain and histidine kinase domain (HK), an...

This paper considers the problem of wear estimation in a standard industrial robot joint. Motivated by the observation that the wear processes in a robot actuator cause an increase of the friction levels in the joint, static friction observations are used to infer the wear levels. An existing static friction model is extended to include the e ects of wear, which are analyzed and modeled. The re...

When pulling a particle in a driven granular fluid with constant force Fex, the probe particle approaches a steady-state average velocity v. This velocity and the corresponding friction coefficient of the probe ζ=Fex/v are obtained within a schematic model of mode-coupling theory and compared to results from event-driven simulations. For small and moderate drag forces, the model describes the s...

Linear motor is one of the most important drive units for high-speed machining centers. Nonlinear friction is an important factor affecting the positioning accuracy of linear motor drive system. One of the most important topics for controlling linear motor is how to accurately estimate the parameters of the friction and effectively compensate it. In this paper, to solve the problem existing in ...

The present study compared the efficacy of ACTH 4-9 analog, methylphenidate, and placebo on attention deficit disorder with 30 (HK) children with attention deficit disorder and psychometric measurements. HK children were randomly placed into three groups, according to body weight, and treated with placebo, methylphenidate, and adrenocorticotropic hormone fractions (ACTH 4-9 analog). The results...

Amaç: Kanser hücrelerinin glikoza duydukları ihtiyaç sonucu solunumla ilgili metabolik yolaklarını yeniden düzenlemesi, kanser hücrelerini normal hücrelerden ayıran önemli değişimlerden biridir ve bu değişim ilk olarak 1920’li yıllarda Otto Warburg tarafından rapor edildiği için “Warburg Fenomeni” bilinir. hücrelerindeki artmış glikoliz, yolağı bir hedefi haline getirir. Glikolizin hız kısıtlay...

BACKGROUND Angioedema without wheals (AE) is a symptom characterised by localised episodes of oedema presumably caused by kinin release from kininogen cleavage. It can result from a hereditary deficiency in C1 Inhibitor (C1Inh), but it can present with normal level of C1Inh. These forms are typically difficult to diagnose although enhanced kinin production is suspected or demonstrated in some c...

Abstract We consider an experimental system consisting of a pendulum, which is free to rotate 360 degrees, attached to a cart. The cart can move in one dimension. We study the effect of friction on the design and performance of a feedback controller, a linear quadratic regulator, that aim to stabilize the pendulum in the upright position. We show that a controller designed using a simple viscou...

In real systems, the phenomena, such as pipe-wall viscoelasticity, unsteady friction or fluid structure interaction induce additional damping and dispersion of transient pressure waves than that defined by classical waterhammer. In this paper, unsteady friction models and viscoelastic damping models will be presented and a theoretical formulation of the viscoelastic damping in piping systems wi...

An adaptive control scheme for emergency braking of vehicles is designed based on a LuGre dynamic model for the tire-road friction. The wheel angular speed and longitudinal vehicle acceleration information are used to design a fast convergence observer to estimate the vehicle velocity and the internal state of the friction model. The unknown parameters of the dynamic friction model are estimate...