Summary Many neurodegenerative disorders, such as Alzheimer's Disease, pertain to or spread from specific sites of the brain. Hence, accurate disease staging or therapy assessment in transgenic model mice demands automated analysis of selected brain regions. To address this need, we have developed an algorithm, termed SliceMap, that enables contextual quantification by mapping anatomical inform...

High-resolution observations of horizontal motions in the penumbra are needed to complement concept penumbrae obtained from spectropolarimetry. Time series intensity images a large sunspot AR 10634 acquired with Swedish Solar Telescope G band and red continuum analysed. The two simultaneous time last six hours five minutes. Horizontal penumbral grains (PGs), structures dark bodies filaments, ou...

A digital tool is presented and made available for the rapid structural assessment of historic masonry domes. It especially suited domes that present long meridian cracks; ergo partitioned slices governed by a pushing failure mode. The proposed procedure considers Heyman’s no-tension mechanical model has been implemented within user-friendly visual programming environment. numerical approach in...

This paper presents a method for the accurate and computationally efficient alignment of 2-D slices that form a 3-D volume. Alignment incorporates object shape information and is achieved by evaluating the forces acting upon pairs of slices whose object outline points are connected by a system of springs under tension. Experimental results on medical and synthetic 3-D images prove the efficienc...

We describe a new algorithm we have developed for making partially hollow layered parts with thin, dense walls of approximately uniform thickness, for faster build times and reduced material usage. We have implemented our algorithm on a fused deposition modeling (FDM) machine, using separate build volumes for a loosely filled interior and a thin, solid, exterior wall. The build volumes are deri...

White matter lesions are common pathological findings in MR tomograms of elderly subjects. These lesions are typically caused by small vessel diseases (e.g., due to hypertension, diabetes). In this paper, we introduce an automatic algorithm for segmentation of white matter lesions from volumetric MR images. In the literature, there are methods based on multi-channel MR images, which obtain good...

To estimate the locations and intensities of pixels that would appear in the nonexistent int,ermediate slices. This paper presents a new method for generation of the missing medical slices from give two slices. It uses the contours of organs as the control paramet,ers to the intensity information in t,he physical gaps of serial medical slices. The snake model are used for generating the control...

PURPOSE Melatonin's function in human vision is far from understood, in part because of the lack of information on its cellular targets. Therefore, expression and localization of the MT(1) melatonin receptor in human retina was examined. METHODS Postmortem nonpathologic human eyes from nine donors were investigated, three by reverse transcription-polymerase chain reaction (RT-PCR) for MT(1) a...