Objective: To survey the different aspects of penile morphology among a sample of Egyptian males (normal, congenital curvature, etc.) and their relation to erectile dysfunction. Patients and Methods: A sample of 110 male subjects (age ranges from 20–36 years) was selected from our private centre to participate in our study. Although nearly half of them (54 subjects, 49%) had congenital penile a...

Erectile dysfunction is a serious medical problem because it directly affects the sex life of man, but also has an overall effect on his self-esteem and social behaviour.
 Pathophysiologically, erectile may be due to factors vascular origin, anatomical structural features, neurological disorders, hormonal problems, drug-induced or iatrogenic trauma. The so-called psychogenic not uncommon. ...

The present study was undertaken to evaluate the endocrinal causes of infertility in women .Infertility affects 10-15% 0f couples 0f reproductive age groups and female factor is responsible for 40 – 50 %of cases , most common causes of female infertility are ovulatory dysfunction and thyroid hormone ,and estrogen ,progesterone ,and serum Prolactin dysfunction . Estimation of estrogens,progester...

BACKGROUND Giant internal carotid artery (ICA) aneurysms extending into the sellar region, mimicking pituitary tumors, and causing pituitary dysfunction are relatively rare. Open surgery or endovascular treatment can treat these aneurysms, but achieving recovery of endocrine function is difficult. CASE DESCRIPTION A 56-year-old man presented with giant aneurysm of the ICA causing pituitary im...

Ischemic heart disease is the leading cause of morbidity and mortality in a worldwide epidemic. Myocardial ischemia is characterized by an imbalance between myocardial oxygen supply and demand, causing cardiac dysfunction, arrhythmias, myocardial infarction, and sudden death. Various clinical ischemic manifestations are caused by obstruction of coronary blood flow by coronary plaques, thrombosi...

The classical etiology of erectile dysfunction (ED) comprises aging and vascular, neurogenic, psychological and hormonal components. Recent studies have shown that ED can be the forerunner of serious cardiovascular disturbances. It has also been reported that peripheral neuropathy and microvascular injuries caused by pathophysiological changes in patients with diabetes and obesity lead to ED in...

With advancing age, peripheral conduit and resistance arteries lose the ability to effectively dilate owing to endothelial dysfunction. This vascular senescence contributes to increased risk of cardiovascular disease (CVD) with aging. L-arginine plays a role in numerous physiological processes including nitrogen detoxification, immunocompetence, growth hormone (GH) secretion, and insulin secret...

Reproductive disorders are unusually common among women and men with epilepsy. They are generally associated with and may be the consequence of reproductive endocrine disorders. Both epilepsy itself and antiepileptic drug use have been implicated in their pathophysiology. This review focuses on how temporolimbic dysfunction in epilepsy may disrupt normal neuroendocrine regulation and promote th...

Sexual problems are widespread among female cancer patients and survivors. Dysfunction may result from various oncologic therapies such as surgery, radiation therapy, chemotherapy, hormonal manipulation, and cytostatic medication. Additionally, psychologic distress that the patient or her partner experiences during diagnosis and treatment of malignancy can impair a healthy female sexual respons...

Diabetes mellitus, when producing hyperglycemia, as well as angiopathic, vasculopathic, and neuropathic complications, poses a threat to the function and viability of sexual arousal and intercourse at similar and different levels in males and females. Males are faced with hypogonadism, depression and anxiety, affecting their sexual arousal desire. Male intercourse may be impaired by erectile dy...