Fertility is an important predictor of maternal mortality: high fertility levels being associated with high maternal mortality. Factors like use of contraception, fertility preferences are empirically shown to influence fertility levels. Choosing a method of birth control, its effectiveness and safety are the key considerations. Objectives of the study were to determine the proportion of women ...

KEY CLINICAL MESSAGE The clinical course of our patient, who sustained remission status for at least 18 months highlights the chance of long-term hormonal and tumor remission and demonstrates the efficacy and safety of discontinuation of temozolomide therapy. Prospective studies are required in order to define predictors of long-term remission of this promising therapeutic modality.

A solid breast mass that decreases in size over time without treatment is generally felt to be inconsistent with a diagnosis of malignancy. We describe a case where this dogma proves to be incorrect. Mammographic features of a mass, along with the patient's clinical hormonal status, need to be considered along with size characteristics.

BACKGROUND The aim of this study was to evaluate the prognostic implication of asphericity (ASP); spatial irregularity; of pretherapeutic F 2-deoxy-2-fluoro-D-glucose (F FDG) tumor uptake in patients with invasive ductal carcinoma (IDC) of the breast. METHODS One hundred thirty-one female IDC patients (mean age = 48.1 ± 10.4 years), with pathological tumor size greater than 2 cm were retrospe...

The objective of this study was to evaluate the impact of hormonal status and bacterial vaginosis (BV) on the glycosidases present and glycosylation changes as assessed by lectin binding to cervicovaginal lavage constituents. Frozen cervicovaginal lavage samples from a completed study examining the impact of reproductive hormones on the physicochemical properties of vaginal fluid were utilized ...

INTRODUCTION The breast cancer incidence among Singapore women has risen through the years and is now the highest in Asia. Despite efforts to promote a greater awareness of breast cancer among the public, a significant number of patients still present with locally advanced or metastatic breast cancer. Our study aims to evaluate the clinical and pathological characteristics between patients pres...

In the testicular compartment, cAMP response element binding protein (CREB) and cAMP response element modulator (CREM) transcription factors are important transducers of hormonal signals into the induction of gene expression. Selenium (Se) is essential for male fertility. It has been shown earlier in our lab that selenite modulates Nuclear Factor κB, Activator Protein-1 and Stress Activated Pro...

Vänttinen, T, Blomqvist, M, Nyman, K, and Häkkinen, K. Changes in body composition, hormonal status, and physical fitness in 11-, 13-, and 15-year-old Finnish regional youth soccer players during a two-year follow-up. J Strength Cond Res 25(12): 3342–3351, 2011—The purpose of this study was to examine the changes in body composition, hormonal status, and physical fitness in 10.8 6 0.3-year-old ...

Hormonal and reproductive factors modulate bioavailable estrogen to influence endometrial cancer risk. Estrogen affects the microsatellite status of tumors, but the relation between these estrogen-related factors and microsatellite instability (MSI) status of endometrial tumors is not known. We evaluated associations between hormonal and reproductive factors and risks of microsatellite stable (...

Hormonal contraception has recently drawn the attention of both national and international Health Organizations mainly because of new data on the risk of venous and arterial thrombosis. This has, fortunately, not led to a 'pill scare' as happened in 1996 when controversy arose with respect to the thrombotic risk of third versus second -generation pills. This time, evidence on the thrombotic ris...