Background: While praised for its benefits in treating symptoms related to menopausal changes, hormone replacement therapy (HRT) has been associated with an increased risk hormone-dependent cancer development, particularly endometrial and breast. Few studies have elucidated the relationship between HRT cessation receptor-positive breast proliferation. We report herein, best of our knowledge, fi...

This review is concerned with the psychosocial functioning and the quality of life in patients with pituitary insufficiency who are receiving conventional hormone replacement therapy. The possible negative effects of pituitary surgery, treatment with irradiation, and suboptimal replacement regimens with hormones other than growth hormone on mood, behaviour and cognitive functioning are discusse...

We describe a patient who experienced diffuse, treatment-refractory facial inflammatory reaction following the injection of calcium hydroxylapatite with lidocaine. The was attributed to undiagnosed Hashimoto's thyroiditis. Exogenous thyroid hormone replacement therapy rapidly resolved inflammation associated this type autoimmune hypothyroidism.

Growth hormone as therapy for adults with growth hormone deficiency has not been universally accepted by endocrinologists who treat adult patients. The following are addressed in this commentary: the evidence on safety and efficacy in the literature supporting the idea that growth hormone should be offered as replacement therapy to adults who are growth hormone deficient; common concerns of the...

Hypothyroidism was the first endocrine disorder treated by replacement with the deficient hormone, in the form of extracts of animal thyroid glands. Subsequently, the development of purified thyroid hormone preparations and greater understanding of thyroid physiology have made it possible to mimic the function of the normal thyroid gland with thyroid hormone replacement therapy. Thyroid hormone...

Hormone replacement therapy involves restoring estrogen (female hormone) to body when levels are diminished. Menopause is the most common cause of low estrogen levels. During menopause ovaries (glands that produce eggs and hormones) stop producing estrogen and body no longer menstruate. Women who have had their ovaries surgically removed have decreased levels of estrogen and experience the same...

Journal of Family Planning and Reproductive Health Care 2004: 30(1) 11 Mosca L, Collins P, Herrington DM, et al. Hormone replacement therapy and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 2001; 104: 499–503. 12 Shumaker SA, Legault C, Rapp SR, et al Estrogen plus progestin and the incidence of dementia and mild cognitive imp...

thyroid tissue located within the upper airway has received only sparse attention in the english literature. aberrant benign thyroid masses may present as either an unrelated autopsy finding or with symptoms such as dyspnea, hemoptysis or adult -onset asthma. there is no place for medical management in the therapy of these lesions, although the appropriate surgical procedure is not clearly esta...

OBJECTIVE To determine effects of five years of treatment with an oral continuous combined regimen of 2 mg 17beta-oestradiol and 1 mg norethisterone acetate on endometrial histology in postmenopausal women. DESIGN Follow up study in postmenopausal women. SETTING 31 menopause clinics in the United Kingdom. PARTICIPANTS 534 postmenopausal women, all with an intact uterus, who had completed ...

INTRODUCTION The improved survival of children with brain tumors has increased concerns about treatment-related sequelae. Growth hormone deficiency is frequently observed after craniospinal irradiation for medulloblastoma. It has been widely reported that growth hormone replacement therapy does not increase the risk of second tumors, but there are reports in the literature of growth hormone, an...