The proportional diierentiation model provides the network operator with thètuning knobs' for adjusting the per-hop QoS ratios between classes, independent of the class loads. This paper applies the proportional model in the diierentiation of queueing delays, and investigates appropriate packet scheduling mechanisms. The second part of this work 2] considers the corresponding loss rate diierent...

BACKGROUND AND PURPOSE Rapamycin, which is used clinically to treat graft rejection, has also been proposed to have an effect on metabolic syndrome; however, very little information is available on its effects in lean animals/humans. The purpose of this study was to characterize further the effects of the continuous use of rapamycin on glucose homeostasis in lean C57BL6/J mice. EXPERIMENTAL A...

This study aims to characterize diet-dependent amino acid metabolism by linking profiles of amino acids concentrations ("aminograms") with transcript datasets through the analysis of correlation. We used a dietary model of protein restriction-to-excess, where rats were fed diets with different levels of casein (5, 10, 15, 20, 30, 50, and 70%) for 2 wk. Twenty-five different amino acids in the p...

In vitro and in vivo studies were undertaken utilizing an established rat glioma cell line (C6) to compare the phototoxicity characteristics of aluminium tetrasulfonated phthalocyanine (AlSPc), zinc tetrasulfonated phthalocyanine (ZnSPc) and haematoporphyrin derivative (HpD). AlSPc and ZnSPc were inherently less cytotoxic in the dark compared to HpD with 50% colony survival at 275, 355 and 14 m...

Bayesian inference about small areas is of considerable current interest, and simultaneous intervals for the parameters for the areas are needed because these parameters are correlated. This is not usually pursued because with many areas the problem becomes difficult. We describe a method for finding simultaneous credible intervals for a relatively large number of parameters, each corresponding...

In our previous study, as natural food colorants and antioxidants, the color and content stabilities of Schisandra chinensis (S. chinensis) anthocyanins were investigated. In this work, the purification process parameters of S. chinensis anthocyanins using a macroporous resin and gel filtration chromatography were evaluated. The optimized parameters of static adsorption and desorption were as f...

BACKGROUND With the improved overall survival (OS) of nasopharyngeal carcinoma (NPC) patients, the importance of quality of life (QoL) is increasingly being recognized. For some radiosensitive NPC patients, whether low-dose radiotherapy can improve the QoL without affecting clinical efficacy is unknown. This study aimed to assess the survival rates and QoL of NPC patients treated with 50 Gy rad...

Transport of preproteins into the mitochondrial matrix requires the presequence translocase of the inner membrane (TIM23 complex) and the presequence translocase-associated motor (PAM). The motor consists of five essential subunits, the mitochondrial heat shock protein 70 (mtHsp70) and four cochaperones, the nucleotide exchange-factor Mge1, the translocase-associated fulcrum Tim44, the J-protei...

Huntington's disease (HD) is a neurodegenerative disorder caused by the huntingtin (HTT) gene with expanded CAG repeats. In addition to the apparent brain abnormalities, impairments also occur in peripheral tissues. We previously reported that mutant Huntingtin (mHTT) exists in the liver and causes urea cycle deficiency. A low protein diet (17%) restores urea cycle activity and ameliorates symp...