The improvement of garlic plants (Allium sativum L.) via biotechnological approaches is currently limited by the lack of an applicable direct gene transfer system. In this paper, we present the development of a genetic transformation system using particle bombardment for gene delivery and immature clove-derived callus as the gene target. Plasmid DNA (pBI221.23), containing the selectable "hpt" ...

This paper summarizes recent efforts to evaluate the potential for the formation of a metal matrix nanocomposite (MMNC) by processing two commercial bulk metals of aluminum and magnesium alloy through high-pressure torsion (HPT) at room temperature. After significant evolutions in microstructures, successful fabrication of an Al-Mg hybrid system was demonstrated by observing unique microstructu...

During the last decade, a new view into the molecular mechanisms of chronic kidney disease-mineral bone disorder (CKD-MBD) has been proposed, with fibroblast growth factor 23 (FGF23) as a novel player in the field. Enhanced serum FGF23 levels cause a reduction in serum phosphate, together with calcitriol suppression and consequent hyperparathyroidism (HPT). In contrast, reduced serum FGF23 leve...

Recent studies of transgenic mice and humans have provided compelling evidence for the importance of the hypothalamic melanocortin system in the regulation of energy balance. Energy homeostasis is a balance between food intake (energy input) and energy expenditure. The melanocortin system regulates feeding via effects of the endogenous agonist, alpha-melanocyte stimulating hormone (alpha-MSH) a...

The mechanical properties of engineering materials are key for ensuring safety and reliability. However, the plastic deformation of BMGs is confined to narrow regions in shear bands, which usually result in limited ductilities and catastrophic failures at low homologous temperatures. The quasi-brittle failure and lack of tensile ductility undercut the potential applications of BMGs. In this rep...

Autoimmune polyglandular syndrome (APS) type I is a disorder that consists of three primary diseases: hypoparathyroidism (HPT), adrenocortical insufficiency (ACI) and chronic mucocutaneous candidiasis. Several other disorders may be associated. The diagnosis of APS type I was made in a 16-year-old patient with HPT, Hashimato's thyroiditis and ACI in our department. She has been observed for mor...

This paper reports the effect of high-pressure torsion (HPT) on first hydrogenation LaNi5. We found that, for loose powder, reduction particle size has an increasing incubation time and decreasing hydrogen capacity. A higher amount HPT turns only marginally reduce but no In all cases, dehydrogenation subsequent have same kinetics, irrespective or number turns. Therefore, LaNi5, a beneficial hyd...

An efficient Agrobacterium-mediated genetic transformation protocol has been developed in the present investigation to integrate salinity tolerant gene pea DNA helicase (PDH45) two peanut varieties, Dhaka-1 and BARI Chinabadam-8. Decapitated half-embryo explants of above-mentioned varieties were also used develop a compatible vitro regeneration system. MS medium supplemented with 5.0 mg/l BAP 0...

Abstract. Rifhani NF, Apriana A, Sisharmini Santoso TJ, Trijatmiko KR, Slamet-Loedin IH, Yunus A. 2023. Construction of the CRISPR/Cas9 module and genetic transformation aromatic rice cv. Mentik Wangi for developing bacterial leaf blight resistance. Biodiversitas 24: 3258-3268.Rice is a local that susceptible to pests diseases, such as (BLB) caused by Xanthomonas oryzae(Xoo). This bacteria can ...