Cad. Saúde Pública, Rio de Janeiro, 29 Sup:S4-S6, 2013 Health technology assessment (HTA) focuses on understanding the clinical, economic, environmental, social, political, and legal implications of new technologies, or changes in established ones. This multidisciplinary field can provide various decision-makers with hierarchical analyses of the available options for health policy implementatio...

While the Health Technology Assessment (HTA) community has acknowledged the importance of public and consumer involvement in the HTA process, very few studies have examined how technology-related findings may be reported by the media to the broader public. This paper compares the content of press articles with the content of three Canadian HTA reports that respectively assess electroconvulsive ...

The Pan American Health Organization (PAHO), Regional Office of the World Health Organization (WHO) for the Americas, has tried to promote health technology assessment (HTA) in Latin America for 25 years. A certain awareness of HTA developed in several countries because of these efforts. In the late 1990's, there was a strong movement for health reform in Latin America, and HTA became part of t...

BACKGROUND In an era of a growing economic pressure for all health systems, the interest for "disinvestment" in healthcare increased. In this context, evidence based approaches such as Health Technology Assessment (HTA) are needed both to invest and to disinvest in health technologies. In order to investigate the extent of application of HTA in this field, methodological projects/frameworks, ca...

BACKGROUND Decision-analytic modelling (DAM) has become a widespread method in health technology assessments (HTA), but the extent to which modelling is used differs among international HTA institutions. In Germany, the use of DAM is optional within HTAs of the German Institute of Medical Documentation and Information (DIMDI). Our study examines the use of DAM in DIMDI HTA reports and its effec...

Microbial amino acid biosynthesis is a proven yet underexploited target of antibiotics. The biosynthesis of methionine in particular has been shown to be susceptible to small-molecule inhibition in fungi. The first committed step in Met biosynthesis is the acylation of homoserine (Hse) by the enzyme homoserine transacetylase (HTA). We have identified the MET2 gene of Cryptococcus neoformans H99...

Introduction The use of Health Technology Assessment (HTA) in hospitals contributes to decision-making, professional training, greater interaction with technical scientific knowledge, resource-saving, and partnerships. Hospitals are strategic for the field clinical management quality care open partnerships national international agencies groups. Despite hospital-based (HB)-HTA movement, incipie...

OBJECTIVES The purpose of this project was to evaluate local decision support tools used in the Danish hospital sector from a theoretical and an empirical point of view. METHODS The use of local decision support was evaluated through questionnaires sent to all county health directors, all hospital managers, and all heads of clinical departments in cardiology, orthopedic surgery, and intensive...

OBJECTIVES The aim of this study was to describe the history and present situation with health technology assessment (HTA) in Israel. METHODS The method used in this study was a historical analysis based mainly on the knowledge of the authors, but supplemented by the published literature. RESULTS HTA originated in Israel as a centralized function conducted under the auspice of research, dev...

Solving linear systems is an important problem for scientific computing. Exploiting parallelism is essential for solving complex systems, and this traditionally involves writing parallel algorithms on top of a library such as MPI. The SPIKE family of algorithms is one well-known example of a parallel solver for linear systems. The Hierarchically Tiled Array data type extends traditional data-pa...