and Laboratory of Regenerative Medicine, Department of Medical Research, and Department of Surgery, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan. Received: June 24, 2015 Accepted: March 16, 2016 Address reprint request and correspondence to: Ying-Hsien Kao, Laboratory of Regenerative Medicine, Department of Medical Research, and Po-Huang Lee, Department of Surgery, E-Da Hospital, No. 1, ...

BACKGROUND We previously established a mesenchymal stem cell line (FMS/PA6-P) from the bone marrow adherent cells of fetal mice. The cell line expresses a higher level of neural cell adhesion molecule and shows greater hematopoiesis-supporting capacity in mice than other murine stromal cell lines. DESIGN AND METHODS Since there is 94% homology between human and murine neural cell adhesion mol...

BACKGROUND The complex process by which lactation is initiated upon neonate delivery remains incompletely understood. Microvesicles (MVs) can transmit microRNAs (miRNAs) into recipient cells to influence cell function, and recent studies have identified miRNAs essential for mammary gland development and lactation. This study aimed to investigate the expression of lactation-related miRNAs in MVs...

Rare hematopoietic stem cell populations are responsible for the transplantation engraftment process. Umbilical cord blood (UCB) is usually processed to total nucleated (TNC), but not mononuclear (MNC) fraction. TNC counts used determine UCB unit storage, release and correlation with time [1]. It has been mentioned in literature that there several factors affect harvesting of cells [2]. was set...

The purpose of this study was to evaluate human umbilical cord blood as an alternative to bone marrow in the provision of transplantable stem/progenitor cells for hematopoietic reconstitution. Although no direct quantitative assay for human hematopoietic repopulating cells is at present available, the granulocyte-macrophage progenitor cell (CFU-GM) assay has been used with success as a valid in...