We examined the behavior of phenylalanine in high-temperature water (HTW) at 220, 250, 280, and 350 °C. Under these conditions, the major product is phenylethylamine. The minor products include styrene and phenylethanol (1-phenylethanol and 2-phenylethanol), which appear at higher temperatures and longer batch holding times. Phenylethylamine forms via decarboxylation of phenylalanine, styrene f...

The nucleation of the C-S-H gel is a complex process, key to controlling hydration kinetics and microstructure development cement. In this paper, mechanism for crystallization step during non-classical proposed explored by atomistic simulation methods. portlandite precursor monolayers undergo chemically induced transformation condensation silicate dimmers, forming monolayers. We studied DFT nud...

Lipid bilayers and biological membranes are freely permeable to CO(2), and yet partial CO(2) pressure in the urine is 3-4-fold higher than in blood. We hypothesized that the responsible permeability barrier to CO(2) resides in the umbrella cell apical membrane of the bladder with its dense array of uroplakin complexes. We found that disrupting the uroplakin layer of the urothelium resulted in w...

Controlled Release Systems in the world. In comparison with other Controlled Release Devices, they have the advantage of their low cost and simple technology, that facilitates their application to an important sector of the population, as well as their safety against the dose dumping (accidental fast release of the whole drug dose). Another advantage of these matrices concerns the drug release ...

Autogenous shrinkage may be a critical issue concerning the use of limestone-calcined clay-cement (LC3) in high-performance concrete and 3D printable cementitious materials, which have relatively low water to binder (W/B) ratio. Adding an internal curing agent, i.e., superabsorbent polymer (SAP), could viable solution this context. However, employing SAP (without adding additional water) also i...

In the recent years, the biophysical properties and presumed physiological role of aquaporins (AQPs) have been expanded to specialized cells where water and solute exchange are crucial traits. Complex but unique processes such as stomatal movement or pollen hydration and germination have been addressed not only by identifying the specific AQP involved but also by studying how these proteins int...

The major hydraulic phase in all the calcium aluminate cements including ciment fondue is CA (CaAl2O4). Once hydrated, it starts to form the hexagonal crystals of CAH10 and C2AH8 that depending on the time and temperature of hydration convert to the cubic crystals of C3AH6 and AH3. The nature, sequence, ...

Protein folding/misfolding in vivo takes place in a highly crowded and confined environment. Such crowded environment can possibly lead to fewer water molecules surrounding a protein of interest than that seen under in vitro conditions wherein typically dilute aqueous solutions are used. When considering the aforesaid cellular characteristics, such as water depletion and macromolecular crowding...

in this study the effect of nano meter size zro2 particles on the microstructure, densification and hydration resistance of magnesite –dolomite refractories was investigated. 0, 2, 4, 6 and 8 wt. % zro2 particles that were added to magnesite –dolomite refractories containing 35 wt. % cao. the hydration resistance was measured by change in the weight of specimens after 72 h at 25℃ and 95% relati...

The effect of ionic and non-ionic excipients and additives as modulators of swelling and erosion kinetics and verapamil HCl release from guar-based matrix tablets was investigated. Tablet dissolution, erosion and water uptake studies were carried out using a modified USP 23 Apparatus 2 method. The kinetics of gel strength and texture development were studied by textural analysis. Near linear dr...