two new potential magnetic resonance imaging contrast agents, gd-hematoporphyrin (gd-h) and gd-tetra-carboranylmethoxyphenyl-porphyrin (gd tcp), were synthesized and applied to nude mice with human melanoma (mm 138) xenografts. these agents showed a high relaxivity because of their greater potential to coordinate water molecules. the reduction of t1 relaxation times of 16 and 21% was observed i...

background: about 90% of the world�s contraceptive users are women. this gender-based usage has occurred due to the emphasis of family planning programs and contraception research. condom, vasectomy and withdrawal are the only male contraception devices available with less assurance for men. for new male contraceptive to have an impact, they must be acceptable to both men and women, as well as ...

In this paper we consider clusters in the ternary systems water–benzyl alcohol and ethanol, ethyl lactate or g-valerolactone as found with the help of dynamic and static light scattering experiments. These ternary mixtures are powerful solvent media and consist only of low-toxic solvents of natural origin. In a recent work we have shown that surfactantless microemulsions are formed in the water...

In the preformulation study physical compatibility of the drug-excipient was screened and compatibility was observed between Zaltoprofen and selected solubilizers. In the drug solubilizers interference study no interference was observed in UV spectrophometric analysis of Zaltoprofen in presence of employed solubilizers. Aqueous solubility of Zaltoprofen was found 0.028 mg/ml. The solubilizers s...