Ultrasonographic measurements of the intima-media thickness (IMT) of common carotid arteries (CCA) were taken in 50 patients with familial hypercholesterolaemia (FH) and 57 patients with non-familial hypercholesterolemia (NFH). The lipid profile, body mass index (BMI) and waist-hip ratio (WHR) of each patient were recorded. In FH patients, the IMT was significantly higher in overweight and elev...

Patients with hypercholesterolaemia are often treated with the antimicrobial agent neomycin. Such treatment is potentially dangerous, however, as it may favour the emergence of multiresistant, R-factor-carrying, enteric bacteria among the intestinal flora. In 11 out of 14 patients who had received neomycin for three months to eight years most of the faecal coliforms were resistant to at least f...

Familial hypercholesterolaemia (FH) is underdiagnosed globally, and in Malaysia. FH associated with elevated levels of low-density lipoproteins (LDL-C), predisposes an individual to premature cardiovascular disease, including the life threatening clinical manifestations such as acute ST-elevation myocardial infarction (STEMI). Patients admitted STEMI Malaysia are comparatively younger than thos...