Tautomerization is a fundamental chemical reaction which involves the relocation of proton in reactants. Studying optical properties tautomeric species challenging because ensemble averaging. Many molecules, such as porphines, porphycenes, or phenanthroperylene quinones, exhibit reorientation transition dipole moment (TDM) during tautomerization, can be directly observed single-molecule experim...

Failure of conventional therapies to alleviate glioblastoma (GBM) fosters search for novel therapeutic strategies. These include epigenetic modulators as histone deacetylase inhibitors (HDACi), which relax abnormally compact tumor cell chromatin organization, enabling cells to overcome blockage in differentiation. However, in clinical settings, HDACi efficacy is confined to subsets of hematolog...