A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. Plain digital radiograp...

INTRODUCTION Although the majority of patients with primary hyperparathyroidism have a relatively asymptomatic benign disorder, there are patients who have a more aggressive disorder. CLINICAL PICTURE We report a case of primary hyperparathyroidism presenting during pregnancy complicated by antepartum haemorrhage and severe prematurity. The diagnosis was made postpartum, when her problems rap...

Three cases of primary hyperparathyroidism presented as central giant cell granuloma of the jaw bones with various clinical manifestations and systemic background of the patients. Generally the mandible affected more by these lesions in this report two of the cases affect the maxilla, while the third case affects both upper and lower jaws. The diagnosis was confirmed by radiographical and labor...

The deficiency of vitamin D is public among hemodialysis (HD) patients and a key factor in the development secondary hyperparathyroidism (SHPT). Secondary currently accomplished by lowering circulating phosphate levels with parathyroid hormone (PTH), analogs, oral binders. current study aim was to assess efficacy cholecalciferol management concomitant deficiency/insufficiency. A total 53 were t...

Primary hyperparathyroidism is a disease characterized by excessive production of parathyroid hormone (PTH), which is due to a parathyroid adenoma in 85% of cases. An atypical parathyroid adenoma, with some histopathological features of parathyroid carcinoma, may be found in some of the cases, although it may not fulfill all the criteria for this diagnosis. Neurofibromatosis type 1 (NF1) is an ...

Patients with multiple endocrine neoplasia (MEN) type 2A develop medullary thyroid cancer, which is associated with poor prognosis in its metastatic stage. Hyperparathyroidism is a common finding in both MEN 1 and 2. We report a 68-year-old patient diagnosed clinically with MEN 1 based on the presence of hyperparathyroidism and pituitary Cushing's disease with no supporting genetic evidence. T...

Hyperparathyroidism is the commonest presenting feature in multiple endocrine adenomatosis Type I (MEA Type I), the other manifestations may be delayed for many years or appear only in relatives. A family now diagnosed as MEA Type I, who was previously thought, in 1965, to have familial hyperparathyroidism due to chief cell hyperplasia is now described. The importance is stressed of family surv...

Normocalcemic Primary Hyperparathyroidism (NC-PHPT) is a clinical entity characterized by normal serum calcium and persistently elevated parathyroid (PTH) levels. These patients have no obvious causes for secondary hyperparathyroidism such as vitamin D deficiency and renal insufficiency [1,2-16,17]. None of the patients had clear evidence of gastrointestinal disease. Although the entity NC-PHPT...

Brown tumors are focal bone lesions, encountered in patients with uncontrolled hyperparathyroidism. They can be located in any part of the skeleton. Clinically significant lesions in the craniofacial bones are rare. Craniofacial involvement may cause facial disfiguration and compromise social ease of the patient and normal functions, such as chewing, talking, and breathing. In this case report,...