نتایج جستجو برای: hypnotics and sedatives

تعداد نتایج: 16827348  

Journal: :British journal of anaesthesia 2008
R Duarte A McNeill G Drummond B Tiplady

BACKGROUND Anaesthetics which work by different mechanisms may have different patterns of effect. Measurement of these patterns thus may elucidate their mechanisms of action and allow therapeutic choices between the agents. METHODS We compared the effects of ethanol (approximately 80 mg per 100 ml), and different end-tidal concentrations of nitrous oxide (15% and 25%) and sevoflurane (0.3% an...

2015
Sweta V. Jha Ashok M. Bhagwat Nancy. S. Pandita

Introduction: Nardostachys jatamansi DC. is an important ayurvedic plant. The root and rhizome contain active compounds with carminative, sedative, antispasmodic and tranquilizing properties. It is also used as an insect repellent. Essential oil from the drug shows antimicrobial activity against a number of microorganisms. Method: The present study comprises microscopic and macroscopic studies,...

2017
Sooil Shin Seungoh Kim

Patients with severe gag reflex (SGR) have difficulty getting the treatment they require in local clinics, and many tend to postpone the start of their treatment. To address this problem, dentists have used behavioral techniques and/or pharmacological techniques for treatment. Among the pharmacological methods available, propofol IV sedation is preferred over general anesthesia because it is a ...

2015
Eli Oda Sheiner Michael Lifshitz Amir Raz

Placebo response shares phenomenology and likely overlaps with substrates of cognition and personality. However, inconsistent findings abound regarding the potential link between suggestibility and responding to placebos. Here we directly probe whether suggestibility of the hypnotic type influences placebo response. Fifty healthy undergraduates underwent a standard measure of hypnotic suggestib...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2000
M Denda T Tsuchiya P M Elias K R Feingold

Recent studies have shown that psychological stress can influence cutaneous barrier function, suggesting that this form of stress could trigger or aggravate skin disease. In the present study, we demonstrate that transfer of hairless mice to a different cage delays barrier recovery rates. Pretreatment with a phenothiazine sedative, chlorpromazine, before transfer of animals restored the kinetic...

Journal: :Journal of psychiatric research 2016
Jeffery Newell Jerome A Yesavage Joy L Taylor Helena C Kraemer Cynthia A Munro Leah Friedman Paul B Rosenberg Michelle Madore Steven Z Chao D P Devanand Lea T Drye Jacobo E Mintzer Bruce G Pollock Anton P Porsteinsson Lon S Schneider David M Shade Daniel Weintraub Constantine G Lyketsos Art Noda

BACKGROUND We found a benefit of citalopram for agitation in the Citalopram for Agitation in Alzheimer's Disease study (CitAD), and wondered if this was mediated by a sedative effect. CitAD was a randomized, placebo-controlled, double-blind, parallel group trial conducted at 8 academic centers in the United States and Canada from August 2009 to January 2013. One hundred sixty-two participants w...

2017
James Begbie

The attention of the profession in this country, was not, I believe, particularly called to the medicinal properties of the Stramonium till Dr Marcet, in an interesting paper, read before the Medical and Chirurgical Society of London, in June 1816, and published in their Transactions *, detailed the ^results of his experience of its use. Storck, it is true, so early as 1762, in a pamphlet publi...

Journal: :Therapeutic drug monitoring 2004
Jean-Pierre Goullé Jean-Pierre Anger

Amnesia following sedative-hypnotic drug exposure is discussed. Anterograde amnesia clearly occurs with many benzodiazepines. Several drugs are assessed: benzodiazepines and two hypnotics in particular that are structurally unrelated to the benzodiazepines but share some of their properties: zolpidem and zopiclone. The amnesic effects of these drugs are described, memory process, biology of mem...

2017
Jing Gennie Wang Emilie Belley-Coté Lisa Burry Mark Duffett Timothy Karachi Dan Perri Waleed Alhazzani Frederick D’Aragon Hannah Wunsch Bram Rochwerg

BACKGROUND This systematic review and meta-analysis investigates the efficacy and safety of clonidine as a sedative in critically ill patients requiring invasive mechanical ventilation. METHODS We performed a comprehensive search of MEDLINE, EMBASE, CINAHL and the Cochrane trial registry. We identified RCTs that compared clonidine to any non-clonidine regimen in critically ill patients, exclu...

Journal: :Anesthesiology 2013
Michael A Frölich Kui Zhang Timothy J Ness

BACKGROUND Sedation or anesthesia is used to facilitate many cases of an estimated 45 million diagnostic and therapeutic medical procedures in the United States. Preclinical studies have called attention to the possibility that sedative-hypnotic drugs can increase pain perception, but whether this observation holds true in humans and whether pain-modulating effects are agent-specific or charact...

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