Over a 2-month period, 200 type 1 diabetic patients attending a paediatric diabetic clinic in Cairo, Egypt were screened for anaemia and other complications of diabetes. The mean age was 11.2 years and the mean duration of diabetes was 4.0 years. Anaemia was diagnosed in 75 patients (37.5%) overall: 45 had microcytic hypochromic anaemia, 18 normocytic normochromic and 12 macrocytic hyperchromic...

An inherited hypochromic microcytic anemia transmitted in an autosomal manner has been observed in three generations of an English family. Affected members had the hallmarks of heterozygous beta-thalassemia, ie, elevated levels of hemoglobin A2 and imbalanced globin chain synthesis. However, despite extensive sequence analysis, no mutations could be found in or around the beta-globin genes of e...

Deletion of the murine &major globin gene on chromosome 7 causes a severe, hypochromic anemia in homozygous mice. We show that over 50% of the homozygous mice die either in utero or at birth. Mice heterozygous for the deletion have a slightly increased percentage of reticulocytes when compared with normal mice, but no clinical anemia. As a therapeutic measure, we transplanted 2 X 10' congenic g...

OBJECTIVE To describe a rare case of thrombocytopenia secondary to iron deficiency. CLINICAL PRESENTATION AND INTERVENTION A 34-year-old woman presented with severe microcytic hypochromic anemia and thrombocytopenia. Her ferritin was 1 ng/dl. A diagnosis of iron deficiency anemia and thrombocytopenia was made and the patient was treated with packed red blood cell transfusion and intravenous i...

PURPOSE Cerebral venous thrombosis (CVT) has a wide spectrum of symptoms and is therefore difficult to diagnose. CVT has been reported to be associated with various etiologies. There are, however, very few reported cases of CVT associated with iron deficiency anemia (IDA), especially in adults. CASE REPORT We reported the case of a female patient with seizure and hemorrhagic infarction due to...

Micellar aggregates have been prepared from chloro­ phyll a. Whereas most detergents including non-ionic, zwitterionic and anionic ones, produce aggregates with long-wavelength shifted and enhanced Q Y absorption, the cationic detergents hexadecyl-trimethylammoniumbromide and hexadecyl-pyridiniumchloride produce complexes with opposite traits: The Q Y absorption is shifted to shorter wavelength...

A study was undertaken to investigate the effect of Salmonella gallinarum endotoxin on clinical symptoms and some haematological changes in mature six-month-old cockerels. Salmonella gallinarum endotoxin caused characteristic clinical symptoms, severe olygocytic hypochromic anaemia, leucocytosis and increased phagocytic function of leucocytes. Heterophilia was associated with relative lyphopeni...

OBJECTIVE Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes. Mutations could be either more commonly deletional or non-deletional. As some deletions (3.7 and 4.2) cause α+-thalassemia, some cause (-20.5, MED, THAI, FIL) α0 -thalassemia. The aim of this study was to determine alpha thalassemia mutations in patients with unsolved hypochromic microcytic ...

Background: Severe acute malnourished children are prone to deranged pathophysiology. Their haematological profile affected mild severe degree. Our study was done observe the of admitted at P.B.M. Hospital Bikaner, Rajasthan. Material And Methods: This prospective observational designed for 178 children. Duration this one year from 01.01.2013 31.12.2013. in special concern Results: showed that ...