The relative contributions of the sympathetic nervous system and the adrenal medullae, the two components of the sympathoadrenal system, to the manifestations of hypoglycemia are largely unknown. We tested the hypothesis that the neurogenic symptoms of hypoglycemia are largely the result of sympathetic neural activation. To do so, we quantitated neurogenic symptoms, as well as norepinephrine (N...

BACKGROUND Our study aims at exploring the hypoglycemic effect, efficacy, and possible mode of action of ethanol extract of Alpinia nigra (EEAN) as an antidiabetic agent in an animal model. METHODS Oral glucose tolerance test (OGTT) was used to identify primary hypoglycemic effect in mice. Three tests (glucose absorption, sucrose absorption, and disaccharidase activity) were carried out by gu...

objective(s) seed of cucumis sativus linn. is one of the herbal remedies has been traditionally used for diabetes mellitus treatment. we studied the effect of hydroalcoholic and buthanolic extract obtained from c. sativus seeds in a model of streptozotocin (stz)-induced diabetic (type i) rats. materials and methods normal and diabetic male wistar rats (stz, 60 mg/kg, intraperitoneal) were treat...

background: the mechanism of hypoglycemic and hypolipidemic activities of pyrus biossieriana buhse leaf extract (pbble) and its phytochemical component arbutin, have not been well determined. the present study was performed to understand the hypoglycemic activity mechanisms of pbble and arbutin more clearly.methods: in vitro enzymatic carbohydrate digestion with pbble and arbutin was assessed u...