freely soluble and hence was rapidly absorbed. Its effect was rapidly felt and almost as rapidly exhausted. Hence there were frequent hypoglycemic reactions which alarmed the patients and sometimes led to their refusing to continue a treatment which appeared to be and was in fact dangerous. In order to avoid sudden falls in blood-sugar various attempts have been made to prolong the action of in...

Preliminary investigations on 14 plant extracts (obtained by ethanolic and aqueous extraction) identified those having high antioxidant and a significant total phenolic content. Antihyperglycemic, α-amylase and α-glucosidase inhibition activities were also observed. A correlation between the antihyperglycemic activity, total phenolic content and antioxidant (DPPH scavenging) activity was establ...

Introduction: Chronic kidney disease (CKD) poses a financial burden on most patients from low/ middle income countries. Glycaemic control with affordable hypoglycemic agents may influence the prognosis of diabetic nephropathy. Objectives: We aimed to compare rates CKD progression and proteinuria in type 2 population response use various agents. Patients Methods: A retrospective cross-sectional ...

Sikkim and Darjeeling Himalayan region is characterized by a rich floral diversity and an equally rich ethnomedicinal tradition. Herbal medicine is the dominant system of medicine practiced by the local tribes of this region for the treatment of diabetes. During the course of the present studies it was found that 37 species of plants belonging to 28 families are used as antidiabetic agents in t...

OBJECTIVES To propose standardized methods for measuring concurrent adherence to multiple related medications and to apply these definitions to a cohort of patients with diabetes mellitus. STUDY DESIGN Retrospective cohort study of 7567 subjects with diabetes prescribed 2 or more classes of oral hypoglycemic agents in 2005. METHODS For each medication class, adherence for each patient was e...

The control over diabetes mellitus depends upon the availability of insulin. Various efforts have been made in the recent past to control / check it. There is an increasing demand to use the natural antidiabetic agents. The literature pertaining to antidiabetic herbs is scattered. The present article is a conglomeration of available indigenous literature. It gives an additional information of l...