Genetic Background and Environment Influence the Effects of Mutations in pykF and Help Reveal Mechanisms Underlying Their Benefit Report Title Resolving the relationship between genotypes and their effects remains a central challenge in the study of adaptation. Although parallel mutations, a signature of adaptation, have been observed a lot in natural and lab-evolved populations, it is unknown ...

abstract background thalassemia is common in the iranian population, and it must be considered in the differential diagnosis of the microcytic hypochromic anemia. the molecular analysis of β-thalassemia is necessary for prenatal molecular diagnosis. α-thalassemia caused by loss of function of either one of the two duplicated α-globin genes or in less frequent non deletion mutations mostly locat...