PURPOSE Inflammatory breast cancer (IBC) is arguably the deadliest form of breast cancer due to its rapid onset and highly invasive nature. IBC carries 5- and 10-year disease-free survival rates of ~45% and <20%, respectively. Multiple studies demonstrate that in comparison with conventional breast cancer, IBC has a unique molecular identity. Here, we have identified platelet-derived growth fac...

according to non-existence of accurate inspection tools on various steps of design and construction of buildings in the past, also due to any change in function of some structures and finally of seismic activities of residential regions of the country, vulnerability assessment of existing structures is necessary. evaluation of vulnerability of the structures is classified in two categories, qua...

well-known seismic design codes have offered an alternative equivalent static procedure for practical purposes instead of verifying design trials with complicated step-y-step dynamic analyses. such a pattern of base-shear distribution over the building height will enforce its special stiffness and strength distribution which is not necessarily best suited for seismic design. the present study, ...

A technical benchmarking study is presented, aimed to evaluate the EU harmonized Romanian seismic assessment code in comparison with its European and U.S. homologues and to identify potential opportunities for its future improvement. The benchmarking procedures are illustrated by parallel seismic assessments, performed, according to the analyzed regulations, on a reinforced concrete frame struc...

this paper assesses the design guidelines of different classification codes for the liquefied natural gas carriers considering the effect of liquid sloshing. with regard the increasing importance of lng carriers in today’s marine transportation, and also considering that the marine accidents involve significant loss, classification societies by regulating national and international standards ai...

This paper deals with the influence of an Intelligent Boom Control (IBC) in forwarders on work operators. The IBC and standard system crane control was measured by use a John Deere harvester forwarder simulator. Two individuals without any practical training two experience took measurements. monitoring included eight different performance indicators. allowed untrained operators to increase thei...

Irregular buildings make up a large portion of  urban infrastructure. Presence of irregularities can be due to architectural and  user changes in building stories. Main objective of this article is evaluate seismic performance of structures with vertical irregularities. Seismic responses are obtained by enveloping peak inelastic responses resulting from pushover analyses according to provided p...

Inflammatory breast cancer (IBC) is the most lethal form of breast cancer, but the basis for its aggressive properties are not fully understood. In this study, we report that high tumoral expression of TIG1 (RARRES1), a functionally undefined membrane protein, confers shorter survival in patients with IBC. TIG1 depletion decreased IBC cell proliferation, migration, and invasion in vitro and inh...