Cortical and subcortical contributions to the processing of emotional speech prosody were evaluated by testing adults with single focal lesions involving the right hemisphere (n=9), adults with basal ganglia damage in idiopathic Parkinson’s disease (n=21), and healthy aging adults (n=33). Participants listened to semantically-anomalous utterances in two conditions (identification, rating) which...

Hereditary haemochromatosis (HH) is a genetic disorder in which abnormal iron handling leads to excessive iron accumulation in systemic tissues. Magnetic resonance imaging studies suggest excess iron deposition in the basal ganglia of patients with HH. The symptoms of neurological complications of HH include cognitive decline, gait difficulties, cerebellar ataxia, and extrapyramidal dysfunction...

Basal ganglia calcification is one of the features of chronic hypocalcaemia.1 However, extensive intracranial symmetrical calcifications outside the basal ganglia have been reported rarely in patients with chronic hypocalcaemia secondary to post-surgical hypoparathyroidism. A 62-year-old woman who underwent subtotal thyroidectomy 15 years ago presented with long-term paraesthesiae in the distal...

We report a case of idiopathic bilateral basal ganglia calcinosis, or Fahr's disease (FD) in a 50 year old patient who developed rapidly progressive behavioural abnormalities and severe neuropsychological impairments, but no movement disorder. Neuropsychological deficits included a severe dysexecutive syndrome, anterograde amnesia, and attentional impairment. Neuropsychiatric features comprised...

A B S T R A C T Introduction:We investigated differential role of cortical and subcortical regions in verbal and non-verbal sound processing in ten patients who were native speakers of Persian with unilateral cortical and/or unilateral and bilateral subcortical lesions and 40 normal speakers as control subjects. Methods: The verbal tasks included monosyllabic, disyllabic dichotic and diotic tas...