OBJECTIVE Amenorrhea is a DSM-IV criterion for the diagnosis of anorexia nervosa (AN). Several studies have reported few differences between patients who meet the full DSM-IV criteria for AN and those who meet all but the amenorrhea criterion. Although this suggests that the absence of menses does not provide critical diagnostic information, many of these studies are limited by small sample siz...

Background: PCOS was a common hormonal disorder caused by hyperandrogenism so the ovaries enlarged with many small follicles appear like cysts. The aetiology still unknown, but mounting evidence suggests that can be complex multigenic strong epigenetic and environmental influences. Therapeutic options include combined oral contraception, antiandrogens, etc. Case Presentation: Ms. N, 17 years ol...

BACKGROUND Chemotherapy-induced amenorrhea is one of long term side effects of adjuvant chemotherapy in patients with breast cancer which may interfere with their future reproductive function. Although amenorrhea is well recognized, the actual incidence following taxanes remains uncertain. METHODS In a cross sectional study, we identified breast cancer patients aged 45 years or younger who we...

AIM To estimate the influence of intensive training on menstrual cycles in female athletes. METHOD The questionnaire was used to determine the time of menarche, and the prevalence of primary and secondary amenorrhea and dysmenorrhea in 72 active female athletes from Zagreb (10 volleyball players, 18 basketball players, 10 ballet dancers, and 34 runners) aged between 15 and 21. The control gro...

BACKGROUND The forkhead transcription factor Foxo3 is a master regulator and potent suppressor of primordial follicle activation. Loss of Foxo3 function in the mouse leads to premature ovarian failure (POF) due to global follicle activation. METHODS AND RESULTS Here, we show that the mouse Foxo3 locus is haploinsufficient, and that Foxo3-/+ females undergo early reproductive senescence consis...

Objective: To determine whether the levonorgestrelreleasing intrauterine system can safely reduce menstrual blood loss and improve quality of life in patients with idiopathic menorrhagia. Study Design: Prospective Multicentre study. Setting: Obstetrics and Gynecology Departments (King Khalid University Hospital-KSA, Enjab Hospital for infertilityUAE and Gulf Medical College and Research Centre-...

BACKGROUND The aim of the present study was to investigate the chromosomal abnormalities and to identify the most prevalent or frequent type of chromosomal abnormalities in cases of amenorrhea from the southern region of India. METHODS A total of 637 cases with amenorrhea were analyzed using G- banding, C-banding, Silver staining, and fluorescence in situ hybridization was done wherever neces...

PURPOSE OF REVIEW We present an update on amenorrhea in adolescent girls and young women. Amenorrhea may herald the onset of estrogen deficiency, which can adversely affect peak bone mass and ultimate risk of osteoporosis. RECENT FINDINGS Adolescence is a critical period for bone accretion. Important modifiable factors that optimize bone accretion during this time are calcium intake, vitamin ...

The problem of infertility is relevant to the whole world, that explaned both by prevalence (at least 50 million couples on planet are diagnosed) and enormous medical, ecoomic, social psychological significance. Another important aspect heterogeneity its causes – about 40% infertile marriages caused female factor, 35% male, 20% a combination male factors 5% have no identified factor. In 2019, A...

gestational choriocarcinoma usually occurs following an intrauterine pregnancy. we report a case of metastatic choriocarcinoma to the left kidney and lungs with long term intermittent amenorrhea and vaginal bleeding after a normal vaginal delivery. a 43 year old rural woman presented with three years intermittent amenorrhea and vaginal bleeding following normal vaginal delivery. she also compla...