The contrast medical imaging is an active research domain in which several coding techniques of the transmit have been proposed to increase the contrast. In this paper, we focus on the continuous coding of the Ultrasound transmits, such as “chirp” sequences, and their insonation on the medium under exploration. We empirically show that there are particular values for the frequency parameters of...

H NMR imaging is a powerful technique for studying the diffusion of pure hydrocarbons (for example benzene and n-hexane) during their adsorption in or desorption from a fixed bed of zeolite crystallites. This technique is used to visualize the progression of the diffusing molecules in the zeolite bed and to determine their intracrystallite diffusion coefficients. More importantly, NMR imaging i...

Although the addition of just the excitation light field at the focus, or of just the fluorescence field at the detector is sufficient for a three- to fivefold resolution increase in 4Pi-fluorescence microscopy, substantial improvements of its optical properties are achieved by exploiting both effects simultaneously. They encompass not only an additional expansion of the optical bandwidth, but ...

We introduce photothermal optical lock-in Optical Coherence Microscopy (poli-OCM), a volumetric imaging technique, which combines the depth sectioning of OCM with the high sensitivity of photothermal microscopy while maintaining the fast acquisition speed inherent to OCM. We report on the detection of single 40 nm gold particles with a 0.5 μm lateral and 2 μm axial resolution over a 50 μm depth...

Cone beam CT (CBCT) is a relatively new imaging modality, which is now widely available to dentists for examining hard tissues in the dental and maxillofacial regions. CBCT gives a three-dimensional depiction of anatomy and pathology, which is similar to medical CT and uses doses generally higher than those used in conventional dental imaging. The European Academy of DentoMaxilloFacial Radiolog...

Zebrafish has emerged as an excellent vertebrate model organism for studies of evolution, development and disease. Due to its external development and optical transparency in embryonic stages, zebrafish offers a major advantage over other vertebrate model organisms by being amenable for microscopic studies of biological processes within their natural environment directly in the living organism....

We had developed Optical Scatter Imaging (OSI) as a method which combines light scattering spectroscopy with microscopic imaging to probe local particle size in situ. Using a variable diameter iris as a Fourier spatial filter, the technique consisted of collecting images that encoded the intensity ratio of wide-to-narrow angle scatter at each pixel in the full field of view. In this paper, we r...

A fundamental goal in biology is to determine how cellular organization is coupled to function. To achieve this goal, a better understanding of organelle composition and structure is needed. Although visualization of cellular organelles using fluorescence or electron microscopy (EM) has become a common tool for the cell biologist, recent advances are providing a clearer picture of the cell than...

A real-time three-dimensional (3D) photoacoustic imaging system was developed for epilepsy imaging in small animals. The system is based on a spherical array containing 192 transducers with a 5 MHz central frequency. The signals from the 192 transducers are amplified by 16 homemade preamplifier boards with 26 dB and multiplexed into a 64 channel data acquisition system. It can record a complete...

TCRT continues to offer to its readers the current advances in OPTICAL BIOPSY. This special section’s focus is presented in four articles in optical imaging area. The salient features of the articles touch upon the use of time and frequency domain in imaging, the use of different wavelengths of several of possible fingerprint molecules in cancer, the role of hypoxia in cancer, the use of key to...