نتایج جستجو برای: immune complex diseases
تعداد نتایج: 1764596 فیلتر نتایج به سال:
Genetic improvement programs may improve disease resistance in animal production. The best-characterized genetic control of disease resistance and immune response in animals is the one associated with the Major Histocompatibility Complex (MHC). The ovine lymphocyte antigenof DRB1 gene encodes cell surface glycoproteins that initiate immune responses by presenting processed antigenic peptides to...
cd40 is recognized as a member of tumor necrosis factor receptor super family. it is expressed by the immune and non-immune cells. its interaction with cd40 ligand (cd154) brings about a regulatory effect on the cellular and humoral immunity. the pathway of cd40-cd154 is influential in various diseases. investigations on such diseases have revealed dimensional mechanisms whereby this route in...
The possibility of breeding or genetically engineering cattle for resistance to disease has tremendous potential for increasing the efficiency of milk and meat production. In cattle and other species, major genes that control humoral and cellular immune responses to a variety of antigens have been mapped to a chromosomal region known as the major histocompatibility complex. However, resistance ...
Multiple experimental investigations have been successful in suggesting the role of heat shock protein as a clinical biomarker and therapeutic target several diseases. All living cells, from simplest prokaryote to most complex multicellular organism, contain proteins-molecular chaperones that are responsible for management unfolded polypeptides within cell. In view fundamental proteins maintena...
The modern biomedical research and healthcare delivery domains have seen an unparalleled increase in the rate of innovation and novel technologies over the past several decades. Catalyzed by paradigm-shifting public and private programs focusing upon the formation and delivery of genomic and personalized medicine, the need for highthroughput and integrative approaches to the collection, managem...
*Please consult the online schedule for this course for the definitive date and time for this lecture. Key Concepts vs Supplementary Information: The syllabus is meant to accompany the lectures and the material covered (other) than that in italics) is considered important to your understanding of the subject. Key items are marked in bold. Supplemental information is marked in italics. Lecture O...
A trait is often of interest by virtue of being either highly desirable, for example intelligence, or highly undesirable, for example cancer. Genetic influence over the trait can be established inmanyways including twin studies, clustering statistics and statistical modelling. Once the existence of a genetic component has been established, the next step is to locate the genes involved. The ease...
Currently, it is generally accepted that multiple sclerosis (MS) is a complex multifactorial disease involving genetic and environmental factors affecting the autoreactive immune responses that lead to damage of myelin. In this respect, intrinsic or extrinsic factors such as emotional, psychological, traumatic, or inflammatory stress as well as a variety of other lifestyle interventions can inf...
Monoclonal antibodies (mAbs), which currently constitute the main class of biotherapeutics, are now recognized as major medical tools that are increasingly being considered to fight severe viral infections. Indeed, the number of antiviral mAbs developed in recent years has grown exponentially. Although their direct effects on viral blunting have been studied in detail, their potential immunomod...
Autophagy-related (ATG) gene products regulate macroautophagy, LC3-associated phagocytosis (LAP) and LC3-dependent extracellular vesicle loading secretion (LDELS). These processes also influence antigen processing for presentation on major histocompatibility complex (MHC) molecules to T cells. Here, I summarize how these different pathways use the macroautophagy machinery, contribute MHC class ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید