Cutaneous manifestations are the most common presenting sign of chronic graft-versus-host disease (cGVHD) and extent cutaneous involvement is also highly correlated with prognosis. Very little understood about underlying pathogenesis underpinning injury at this location, especially contribution keratinocytes other structural skin cells. We performed single-cell RNA-sequencing to compare transcr...

Cryptococcus gattii infections, especially including those with severe clinical manifestations, may be related to underlying host immunologic factors. We present 2 cases with autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF), a key cytokine in macrophage function. Immunologic evaluation for anti-GM-CSF antibodies may be important to inform management and counseling.

361 How to cite this article: Velez AMA, Valencia-Yepes CA, Howard MS. Immunologic markers to arrector pili muscle, blister tissue and vessels in a case of bullous eczema herpeticum. Our Dermatol Online. 2017;8(3):361-363. Submission: 10.10.2016; Acceptance: 01.02.2017 DOI: 10.7241/ourd.20173.105 Immunologic markers to arrector pili muscle, blister tissue and vessels in a case of bullous eczema...

In leprosy, an infection produced by a mycobacterium, M. leprae, which is an obligatory intracellular parasite, it is the cell-mediated immunologic phenomena which intervene as defensive mechanisms, and not circulating antibodies. A high proportion of the general population is immune to the disease. It seems that in each generation there is a small group of persons susceptible to infection who ...