Much of Alzheimer disease (AD) research has been traditionally based on the use of animals, which have been extensively applied in an effort to both improve our understanding of the pathophysiological mechanisms of the disease and to test novel therapeutic approaches. However, decades of such research have not effectively translated into substantial therapeutic success for human patients. Here ...

As technology (particularly smartphone and computer technology) has advanced, sociolinguistic methodology likewise adapted to include remote data collection. Remote methods range from approximating the traditional interview via synchronous video conferencing developing new for asynchronous self-recording (Boyd et al., 2015; Leeman 2020). In this paper, we take a close look at question prompts s...

America's dual interest in social welfare and practical science fueled the emergence of social psychology in the late 19th century. By that century's end, psychologists had presented diverse and sometimes contesting models of social psychology. These varied conceptualizations, however, were challenged by the discipline's growing dedication to the scientific method and experimentation, as well a...

Thermodynamic studies on the bioadsorption of Cr(III) onto Agave lechuguilla biomass were conduced. The experimental results at different temperatures were modeled using the Langmuir and Freundlich isotherms to obtain the characteristic parameters of each model. Both the Freundlich and Langmuir models were found to represent the bioadsorption process. The average adsorption capacities calculate...

BACKGROUND Pretreatment is necessary to reduce biomass recalcitrance and enhance the efficiency of enzymatic saccharification for biofuel production. Ionic liquid (IL) pretreatment has gained a significant interest as a pretreatment process that can reduce cellulose crystallinity and remove lignin, key factors that govern enzyme accessibility. There are several challenges that need to be addres...

Thomas McKeown was a rhetorically powerful critic, from the inside, of the medical profession's mid-20th-century love affair with curative and scientific medicine. He emphasized instead the importance of economic growth, rising living standards, and improved nutrition as the primary sources of most historical improvements in the health of developed nations. This interpretation failed to emphasi...