Basal and LH-RH induced plasma FSH and LH levels were determined longitudinally in 41 patients aged 4 to 22 years with Turner's syndrome and in 4 male patients with prepubertal castration. In 12 patients with Turner's syndrome over 18 yrs of age without pubertal change, basal and LH-RH induced FSH levels studied at age 11--22 yrs were all significantly increased over normal levels. However, som...

To establish the role of hormone receptors in patients with polycystic ovary (PCO), PCO rats were prepared by treating with testosterone propionate (TP). Five-day old immature female rats were subcutaneously injected with 1.25 mg TP in sesame oil. They were then killed at the age of 12 weeks. The ovarian receptors for LH and FSH as well as serum hormone levels were investigated in PCO rats and ...

A luteinizing hormone/follicle-stimulating hormone-releasing hormone (LH/FSH-RH) test was performed in 70 women with amenorrhoea or anovulatory infertility, or both, and a clomiphene stimulation test was also performed in 24 of these patients. Most patients responded to LH/FSH-RH with significant increases in LH and FSH. In women with gonadal dysgenesis or premature ovarian failure exaggerated ...

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women reproductive age group. PCOS has been frequently associated with insulin resistance and obesity. Although cases are obese or overweight, a significant proportion patients have normal body mass index (BMI≤25 kg/m2) that makes diagnostic work up therapeutic approach more difficult. These referred t...

This study was undertaken to investigate age-dependent and postmenopausal changes in the serum levels of anti-Mullerian hormone (AMH), inhibin B, insulin-like growth factor (IGF)-I, IGF-binding protein-3 (IGFBP-3), and follicle-stimulating hormone (FSH), and to determine which of these markers best reflects the aging process in women. A total of 144 women aged 20-59 yr were enrolled in this cro...

OBJECTIVE The objectives of this study were to observe the changes in follicle-stimulating hormone (FSH) and bone mineral density (BMD) in postmenopausal women, to research the relationship between FSH and postmenopausal osteoporosis, and to observe the effects of FSH on osteoclast differentiation in RAW264.7 cells. METHODS We analyzed 248 postmenopausal women with normal bone metabolism. A r...

background: smoking has negative effects on reproductive process. exposing to cigarette smoking (passive smoking) may exert some effects as the direct smoking. objective: the aim of this study was to evaluate the correlation between ovarian response and passive smoking in women who underwent art cycles. materials and methods: one hundred-sixty patients who underwent icsi between 2000 and 2001 w...

Prepubertal (14 days old) and mature (10 to 12 months old) male rats were hemicastrated and killed at selected intervals during a 12-week period to compare the effect of age on acute and chronic pituitary and testicular responses to hemicastration. Testis weight was increased (P less than 0.05) in hemicastrated (HC) prepubertal rats but not in mature rats compared with intact controls. After su...

BACKGROUND This study seeks to determine whether estrogen is able to regulate the expression of heparanase-1 (HPR1) in human endometrium. METHODS HPR1 expression and heparan sulphate (HS) deposition in the endometrium collected in various menstrual phases were analysed by immunohistochemical and immunofluorescence staining, respectively. HPR1 expression in the endometrial cells unexposed or e...

The study was done to investigate the effects of cyclical changes of endogenous sex hormones during different phases of menstrual cycle on Acylation stimulating Protein (ASP) and its correlation with lipid profile parameters in healthy reproductive women. Twenty nine healthy reproductive women with regular menstrual cycles were included in this longitudinal study. The levels of FSH, LH, progest...