IMPORTANCE The extended columellar strut-tip graft was designed to improve nasal tip projection and tip definition in patients undergoing rhinoplasty. OBJECTIVE To determine whether the extended columellar tip graft leads to a true and measurable increase in nasal tip projection or simply gives the illusion of an increase in projection. DESIGN Retrospective case review. The mean time of fol...

This study aimed to characterise viscoelastic properties of different categories of chordae tendineae over a range of frequencies. Dynamic Mechanical Analysis (DMA) was performed using a materials testing machine. Chordae (n=51) were dissected from seven porcine hearts and categorised as basal, marginal, strut or commissural. Chordae were loaded under a sinusoidally varying tensile load at a ra...

OBJECTIVE To develop an easy-to-use tool for decision-making on prophylactic replacement of Björk-Shiley convexo-concave heart valves. DESIGN Decision analysis comparing elective replacement with observation. SETTING Referral centres for patients with artificial heart valves. PATIENTS Quantitative estimates were obtained from a follow up study conducted in The Netherlands, including 2303 ...

OBJECTIVES To determine whether using a fixed-angle locked plate plus a fibular strut autograft to treat humeral surgical neck nonunions can result in improved union. PATIENTS AND METHODS The study cohort included 5 females and 2 males with an average age of 58.4 years (range 45-76) who presented with atrophic nonunion of the surgical neck of the humerus. All patients underwent revision surge...

Cell migration plays a critical role in a wide variety of physiological and pathological phenomena as well as in scaffold-based tissue engineering. Cell migration behavior is known to be governed by biochemical stimuli and cellular interactions. Biophysical processes associated with interactions between the cell and its surrounding extracellular matrix may also play a significant role in regula...

We evaluated the biomechanical properties of two different methods of fixation for unstable fractures of the proximal humerus. Biomechanical testing of the two groups, locking plate alone (LP), and locking plate with a fibular strut graft (LPSG), was performed using seven pairs of human cadaveric humeri. Cyclical loads between 10 N and 80 N at 5 Hz were applied for 1,000,000 cycles. Immediately...

Aims To compare endothelium-dependent vasomotor function and vascular healing 15 months after implantation of two new-generation drug-eluting stents and biovascular scaffolds (BVS). Methods and results A total of 28 patients previously treated with a SYNERGY stent (bioabsorbable polymer everolimus-eluting stents (BP-EES)), a PROMUS stent (persistent polymer everolimus-eluting stents (PP-EES))...

Prosthetic heart valves are a blessing for people with defective heart valves. One type of mechanical heart valve that was manufactured between 1979 and 1985 has been implanted in approximately 86,000 people. Between 500 and 600 of these valves are known to have failed. The failure occurs when a thin wire strut breaks free, see Figure l. The strut has two legs that are attached to the main body...

PURPOSE To evaluate treatment outcome following surgical repair of C3 distal femoral fractures using autogenous fibular strut, cortico-cancellous bone grafting, and Ilizarov ring fixation. METHODS A total of 15 patients with type C3 fractures (supracondylar and intercondylar fractures, with multiplane articular injury) underwent surgical repair at St. John's Medical College Hospital between 1...

Study Design Case report. Objective The aim of this study is to describe a case of vascularized fibula strut graft implanted in the cervicothoracic spine of a patient with neurofibromatosis type 1-related progressive kyphosis. Methods A detailed history examination of the surgical procedures and the results of the follow-up after fibula strut graft implantation were performed. In addition, a re...