Uramustine (or uracil mustard, 5-aminouracil mustard, chlorethaminacil), is an bi-functional alkylating nitrogen mustard agent that utilizes a natural product to carry the nitrogen mustard group to a selective metabolite site. The potential for applying uramustine as a therapeutic drug appeared in the 60’s, where its potential as a treatment tool for metastatic Wilms’s tumor was notes (Wilm’s t...

The experiment was carried out during rabi 2018-19 and 19-20 in the experimental field of College Agriculture, Central Agricultural University, Imphal. Seeds two genotypes Indian mustard viz., CAULC-2 (local cultivar) NRCHB-101 were exposed to three doses (1000, 1100 1200 Gy) gamma rays, concentrations ethyl methanesulphonate (0.3, 0.5 0.7%) alone various combinations (1000Gy + 0.5%, 1100Gy 0.5...

We used an in vitro culture system to investigate the effects of three auxin polar transport inhibitors (9-hydroxyfluorene-9-carboxylic acid, trans-cinnamic acid, and 2,3,5-triiodobenzoic acid) on the development of early globular to heart-shaped stage embryos of Indian mustard (Brassica juncea) plants. Although the effective concentrations vary with the different inhibitors, all of them induce...

This research aimed to use mustard flour as meat binder in processing of beef burgers instead of soybean flour (SF). Effect of addition mustard flour from two mustard varieties, yellow (Sinapis alba) (YMF) or brown (Brassica juncea) (BMF) mustard seed flour at different levels (3 and 6%) on the quality characteristics of beef burger patties was studied. The incorporation of mustard flour as a b...

Allergy to mustard seeds has been reported for years, in many cases as very strong anaphylactic reactions. Recent studies have shown that this allergy is increasing and that mustard allergens can be considered among the most important food allergens, especially in countries where the consumption of mustard seed is high. Clinical studies describing hypersensitivity to mustard are reviewed in thi...

As one of the most important vesicant agents, the destructive properties of mustards on the skin, eyes and respiratory system, combined with a lack of antidote, makes them effective weapons. Such weapons are inexpensive, easily obtainable and frequently stockpiled. Sulphur mustard (mustard gas) has been used as a chemical warfare agent in at least 10 conflicts. In this article, the use of musta...

Stigmatic receptivity restricts the successful pollination in cereal crops. The present study deals with the biochemical test for enzymes producing in stigma of field crops such as Indian mustard, rice and wheat. The alcohol dehydrogenase and hydrogen peroxide assays revealed stigmatic receptivity as a violet color and oxygen bubbles released by the chemical reaction. Therefore, the 2 quick tes...

Most herbivorous insect species are restricted to a narrow taxonomic range of host plant species. Herbivore species that feed on mustard plants and their relatives in the Brassicales have evolved highly efficient detoxification mechanisms that actually prevent toxic mustard oils from forming in the bodies of the animals. However, these mechanisms likely were not present during the initial stage...

Aims: To present 12 new variants of uracil mustard having drug-like properties and cytotoxic functional group, by utilizing uracil mustard (uramustine) as a lead compound. Utilize rigorous substructure and similarity of a molecular scaffold to determine drug like variants. Physicochemical properties determined indicate the variants have favorable drug-likeness. Study Design: Conduct molecular d...