BACKGROUND The present study aimed to estimate the cost of rheumatoid arthritis and its components in a university hospital-based health management organization in Argentina, during the prebiologic era. METHODS A one-year (2002) observational prevalence, cost-of illness study of patients with rheumatoid arthritis from the societal perspective was performed in a hospital-based health managemen...

OBJECTIVE To compare the direct and indirect costs of single dose systemic methotrexate with laparoscopic surgery for the treatment of unruptured ectopic pregnancy. DESIGN A cost minimisation study undertaken alongside a randomised trial. SETTING Departments of Obstetrics and Gynaecology in three hospitals in Auckland, New Zealand. PARTICIPANTS Sixty-two women with an ectopic pregnancy ra...

Cost-of-illness studies measure the economic burden of a disease and estimate the maximum amount that could potentially be saved or gained if a disease were to be eradicated. Direct medical costs and indirect costs are measured using top down and bottom up approaches Human Capital approach, Willingness-to-Pay (WTP) approach and Friction Costs approach respectively. The perspectives may measure ...

Asthma prevalence is increasing and asthma-related costs are likely to increase, but few studies have analysed the relationship of asthma costs and severity. The impact of severity on costs was quantified in a cohort of 318 asthmatic patients followed up prospectively for 1 yr. Patients presenting with a broad range of severity of the disease (intermittent, mild persistent, moderate persistent,...

This study was performed to evaluate the potential costs of a hypothetical novel biological agent (BIO) as a therapy for rheumatoid arthritis (RA), compared with oral methotrexate (MTX) and intramuscular gold (IMG). A decision analysis model was used to compare the total costs of treating a cohort of 10,000 RA patients with each agent for 6 months. Total costs included direct costs and indirect...

OBJECTIVE The prevalence of type 2 diabetes has shown a significant increase in parallel with health care costs. The objective of the Brazilian Study on Diabetes Costs (ESCUDI study) was to estimate direct and indirect costs of type 2 diabetes outpatient care in the Brazilian Public Health Care System. METHODS Data were collected from different levels of health care in eight Brazilian cities ...

In a careful examination of the peer-reviewed literature, brachytherapy emerges as the most costeffective treatment for lowto intermediate-risk prostate cancer, providing superior or equivalent effectiveness at lower overall direct costs to the healthcare payer as well as lower indirect costs (e.g., productivity loss) to the patient. Brachytherapy’s lower overall direct and indirect costs are d...

OBJECTIVE COPD is associated with significant economic burden. The objective of this study was to explore the direct and indirect costs associated with COPD and identify the key cost drivers of disease management in Greece. METHODS A Delphi panel of Greek pulmonologists was conducted, which aimed at eliciting local COPD treatment patterns and resource use. Resource use was translated into cos...

OBJECTIVE To examine the impact of type 2 diabetes on direct and indirect costs and to describe the effect of relevant diabetes-related factors, such as type of treatment or glycaemic control on direct costs. DESIGN Bottom-up excess cost analysis from a societal perspective based on population-based survey data. PARTICIPANTS 9160 observations from 6803 individuals aged 31-96 years (9.6% wit...

background: major thalassemia is an autosomal recessive disease with complications, mortality and serious pathology. today, the life expectancy of patients with major thalassemia has increased along with therapeutic advances. therefore, they need lifelong care, and caring for them would incur many costs. being aware of the patients’ costs can be effective for controlling and managing the costs ...