Background: The efficacy and safety of conversion treatment with sirolimus in renal transplant recipients using the calcineurin inhibitor (CNI) with one or more risk factors was evaluated. Methods: Ninety-three renal transplant recipients were prospectively enrolled. CNIs(CsA and FK506) as main immunosuppressant were converted to SRL immunosuppressant protocol. Rapid conversion with sirolimus w...

BACKGROUND AND OBJECTIVES To determine the prevalence, type and site of the injuries due to tramadol-induced seizures in the patients who had referred after its overdose or use of its therapeutic dose. MATERIAL AND METHODS All patients referring to Loghman Hakim Poison Hospital (February 2009 to April 2010) due to tramadol-induced seizures were included. The patients' data including age, gend...

background: the activity concentrations of some radionuclides in soil samples collected from 20 locations in 8 major towns in oyo state, southwestern nigeria have been determined by gamma-ray spectrometry technique. materials and methods: the activity concentrations were determined using high-purity germanium (hpge) detector (canberra industries inc.). the outdoor absorbed dose rates in air at ...

BACKGROUND Optic Neuritis (ON) is one of the most common clinically isolated syndromes which develops into clinically diagnosed Multiple Sclerosis (CDMS) over time. OBJECTIVE To assess the conversion rate of Iranian patients presenting with idiopathic ON to CDMS as well as monitoring potential demographic and clinical risk factors. METHODS Atotal of 219 patients' medical records of idiopath...

introduction exposure to chronic levels of ionizing radiation could be detrimental to health even at very low doses. calabar free trade zone (cftz) was established to promote export business in nigeria and it is yet to produce exposure data of the zone. materials and methods the zone was divided into three categories depending on the type of business. category a had facilities with manufacturin...

The collective effective dose to the population from all x-ray examinations in Finland in 2005 was estimated. The numbers of x-ray examinations were collected by a questionnaire to the health care units (response rate 100 %). The effective doses in plain radiography were calculated using a Monte Carlo based program (PCXMC), as average values for selected health care units. For computed tomograp...

Beverages stored in lead-crystal glass accumulate extraordinary concentrations of lead. We obtained a lead-crystal decanter manufactured with lead from Australia, where the ratio of 206Pb/207Pb is distinctly different from that in the United States. We sought to determine the bioavailability of crystal-derived lead, using the technique of stable isotope dilution in blood. We conducted a single-...

AIMS This study compared the efficacy and safety of intravenous flecainide and ibutilide for immediate cardioversion of atrial fibrillation (AF). METHODS AND RESULTS We conducted a prospective, randomised trial, including 207 patients with AF of recent onset (< or = 48 h). Flecainide was given over 20 min at a dose of 2 mg/kg body weight (maximum 200 mg), ibutilide was infused at a dose of 1 ...

Opioid rotation has been proposed for management of cancer pain. No studies directly investigating dose equivalence between morphine injection (continuous IV administration) and the transdermal fentanyl patch have been reported. Therefore, we examined dose conversion ratios in patients undergoing opioid rotation from morphine injection to fentanyl patches. The subjects consisted of 45 patients ...