Injectable calcium phosphate (CaP) biomaterial is considered as an injectable bone substitute (IBS). It was developed to minimize invasive surgery in various applications in orthopedic and dental surgery. The IBS considered of a polymer solution mixed with biphasic calcium phosphate (BCP) ceramic particles. Two particle sizes of BCP (40-80 and 80-200μm) were used and the weight ratio was 40%. T...

Long-acting injectable antipsychotics constitute a valuable alternative for the treatment of psychotic disorders, mainly schizophrenia. They assure a more stable drug level, improve treatment compliance, and increase the chances for favorable and long-lasting improvement. Additionally, the long-acting second-generation antipsychotics combine the values of long-acting injectable drugs with the v...

A novel redox-triggered bioinspired hydrogel platform that offers high control over gelation onset and kinetics is presented. This suitable for the development of injectable matrices.

The use of injectable fillers enables facial sculpting through treatment of volume depletion and modeling of facial contours. Injectable fillers are among the most frequently performed minimally invasive cosmetic procedures.However, treatment of the lower third of the face can be challenging and requires expertise in facial anatomy. In this article, the authors provide a comprehensive review of...

The Swiss started heroin prescription trials in 1994, the Dutch in 1998. In the Swiss trials, injectable heroin was provided in the context of substantial mandatory psychosocial and medical treatment, with oral methadone or slow-release heroin available as needed to provide additional stabilization. In the Dutch context, injectable or inhalable heroin was provided as an adjunct to oral methadon...

• DRAXXIN (tulathromycin) Injectable Solution administered as a single subcutaneous (SC) injection was safe and effective for the treatment of experimentally induced Mycoplasma bovis (M. bovis) respiratory infection in calves. • DRAXXIN significantly reduced percentage of days with pyrexia and lung lesions compared with saline. • Animals treated with DRAXXIN gained more weight than animals trea...

The second paragraph beginning on page 2 reads: In this review, we define injectable pharmaceutical coformulations as preparations, and which also maintain their distinct pharmacological properties. These are distinct from the pre-mixed insulins that have been available over the last 50 years (Table 1). It should instead read: In this review, we define injectable pharmaceutical coformulations a...

Injectable depots that respond to exogenous and endogenous stimuli present an attractive strategy for tunable, patient-specific drug delivery. Here, the design of injectable and multimodal degradable hydrogels that respond to externally applied light and physiological stimuli, specifically aqueous and reducing microenvironments, is reported. Rapid hydrogel formation was achieved using a thiol-m...

One of the major problems in the treatment of cardiovascular diseases is the inability of myocardium to self-regenerate. Current therapies are unable to restore the heart's function after myocardial infarction. Myocardial tissue engineering is potentially a key approach to regenerate damaged heart muscle. Myocardial patches are applied surgically, whereas injectable hydrogels provide effective ...