Abdollah Amirfarhangi1, Sam Zeraatian2*, Marjan Hajahmadi3 1-Assistant Professor of Cardiology, Department of Cardiology, Rasoul-e-Akram Medical Center, Iran University of Medical Sciences, Tehran, Iran. 2-Assistant professor of Cardiac Surgery, Department of Cardiac Surgery, Rasoul-e-Akram Medical Center, Iran University of Medical Sciences, Tehran, Iran. 3Assistant Professor of Cardiology, De...

Recent biomechanical studies have shown that an anatomic double-bundle posterior cruciate ligament (PCL) reconstruction is superior in restoring normal knee laxity compared with the conventional single-bundle isometric reconstruction. We describe a modification of an endoscopic PCL reconstruction technique using a double-bundle Y-shaped hamstring tendon graft. A double- or triple-bundle semiten...

BACKGROUND The nuclear transcriptional factor NFkappaB is reported to play an important role in the expression of genes for neutrophil and macrophage chemotactic factors, adhesion molecules, and cell cycle-regulating proteins. In aortocoronary bypass surgery, the saphenous vein often develops vein graft disease. Here, we investigated whether transfection of a cis element decoy oligodeoxynucleot...

BACKGROUND In femoropopliteal bypass surgery, the use of saphenous vein grafts is preferable, but synthetic grafts are widely used above the knee. The objective of this meta-analysis was to assess the long-term patency of femoropopliteal bypass grafts classified as above-knee polytetrafluoroethylene, above-knee saphenous vein, or below-knee saphenous vein. METHODS Studies published from 1986 ...

PURPOSE To describe the diagnosis and morphology of abnormal fistulas between dialysis grafts and adjacent native veins in five patients and to discuss their clinical significance. PATIENTS AND METHODS Five patients with PTFE loop-type forearm dialysis grafts were found to have graft-to-vein fistulas in the presence of venous outflow stenosis or occlusion. Three patients underwent surgical re...

BACKGROUND Graft patency is a fundamental predictor of long-term survival after coronary artery bypass surgery. Left and right internal thoracic artery (arterial) graft patency has been shown to be superior to that of saphenous vein grafts. More recently, the radial artery has been used as an aortocoronary graft, but little is known about the midterm and long-term patency of this conduit. We pe...

BACKGROUND Clinical outcome of surgical revascularization using autologous vein graft is limited by vein graft failure attributable to neointima formation. Platelet-derived growth factor (PDGF) plays a central role in the pathogenesis of vein graft failure. Therefore, we hypothesized that nanoparticle (NP)-mediated drug delivery system of PDGF-receptor (PDGF-R) tyrosine kinase inhibitor (imatin...

High-fidelity recordings of left ventricular (LV) pressure and its corresponding first derivative (dP/dt), electrocardiogram, and systemic arterial pressure were obtained intraoperatively following insertion of aortocoronary saphenous vein bypass grafts in eight men. During sequential 3-min periods, the bypass grafts were, in turn, open, occluded by vascular clamps, and opened by releasing the ...

OBJECTIVE Because late vein graft failure is caused by intimal hyperplasia (IH) and accelerated atherosclerosis, and these processes are thought to be inflammation driven, influx of monocytes is one of the first phenomena seen in IH, we would like to provide direct evidence for a role of the MCP-1 pathway in the development of vein graft disease. METHODS AND RESULTS MCP-1 expression is demons...

Objectives. The purpose of this analysis was to define the factors that predict 3-year graft patency. Background. The success of coronary artery bypass graft surgery (CABG) is dependent on vein graft patency after the operation. It has been well established by a series of Department of Veterans Affairs Cooperative Trials that aspirin (325 mg daily) improves saphenous vein graft patency early (7...