نتایج جستجو برای: insulin therapy
تعداد نتایج: 820216 فیلتر نتایج به سال:
AIM The aim of this study was to determine and compare the effect of treatment with transdermal oestrogen and phytoestrogen on insulin sensitivity and sex hormone-binding globulin (SHBG) levels in healthy postmenopausal women. METHODS Forty-three healthy postmenopausal women aged 68 ± 7 (mean ± SD) years who were not receiving hormonal replacement therapy completed a 3 month randomized drug t...
Aim: The present prospective clinical study was conducted to assess the long‑term spironolactone therapy and its effect with without dietary‑induced weight‑loss, on insulin levels, lipid profile, features in females PCOS (polycystic ovary syndrome). Methods: included 22 12 normal weight 10 obese within age of 17-32 years having symptoms including hyperandrogenism or biochemical evidence amenorr...
OBJECTIVE To describe insulin persistence among patients with type 2 diabetes initiating insulin therapy with basal insulin or insulin mixtures and determine factors associated with nonpersistence. RESEARCH DESIGN AND METHODS The Thomson Reuters MarketScan((R)) databases were used to retrospectively analyze insulin-naïve patients with type 2 diabetes by initiating insulin therapy. Insulin use...
BACKGROUND The objective was to compare the efficacy and safety of adding low-dose rosiglitazone (2 or 4 mg/d) to insulin therapy vs continued insulin monotherapy in patients with type 2 diabetes mellitus who were unable to achieve glycemic control with insulin therapy alone. METHODS In this 24-week, double-blind study, 630 individuals with type 2 diabetes mellitus that was inadequately contr...
Approximately 30% to 40% of women with gestational diabetes (GDM) receive insulin therapy, and the multiple daily injection (MDI) regimen a combination basal prandial is generally used, as in cases prepregnancy diabetes. We developed simple (SII) regimen, which one or two injected doses are for mild GDM who require therapy. The present study explored whether not SII effective MDI preventing fet...
Background: Research shows that tight glycemic control is a major factor in forestalling the microvascular and macrovascular complications that accompany diabetes mellitus (DM). Recent evidence shows that earlier use of insulin therapy is beneficial for people who are at higher risk for these complications because it provides more effective glycemic control. Yet, some patients either do not adh...
CONTEXT Corticosteroid therapy induces potentially detrimental hyperglycemia in septic shock. In addition, the benefit of adding fludrocortisone in this setting is unclear. OBJECTIVES To test the efficacy of intensive insulin therapy in patients whose septic shock was treated with hydrocortisone and to assess, as a secondary objective, the benefit of fludrocortisone. DESIGN, SETTING, AND PA...
BACKGROUND Optimal treatment for patients with both type 2 diabetes mellitus and stable ischemic heart disease has not been established. METHODS We randomly assigned 2368 patients with both type 2 diabetes and heart disease to undergo either prompt revascularization with intensive medical therapy or intensive medical therapy alone and to undergo either insulin-sensitization or insulin-provisi...
OBJECTIVE The determinants of insulin-associated weight gain in type 2 diabetes mellitus (T2DM) are partly unknown. Therefore, we conducted a prospective study to identify predictors of insulin-associated weight gain. RESEARCH DESIGN AND METHODS In patients with T2DM, we assessed physical activity by accelerometry and measured diabetes-related distress by questionnaires before and 6 and 12 mo...
Diabetes Technology Society convened a panel of insulin pump experts in Bethesda, Maryland, on November 12, 2008, at the request of the Food and Drug Administration. The group consisted of physicians, nurses, diabetes educators, and engineers from across the United States. The panel members (1) discussed safety features of insulin pump therapy and (2) recommended adjustments to current insulin ...
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