نتایج جستجو برای: intercalative binding mode
تعداد نتایج: 632680 فیلتر نتایج به سال:
پروژه حاضر ضمن بررسی و تحلیل پروسه کنترل کیفی، به ارائه نرم افزاری به منظور پردازش تصویر فانتوم کنترل کیفی دستگاه سونوگرافی b-mode می پردازد. این نرم افزار برای استخراج پارامتر های کنترل کیفی دستگاه سونوگرافی b-mode مورد استفاده قرار خواهد گرفت. پارامترهای کنترل کیفی مورد بررسی در این پروژه عبارتند از : اندازه گیری عمق نفوذ موج ماورا صوت بررسی توان دستگاه دراندازه گیری فواصل عمقی بررسی ت...
Herein, we discuss the synthesis, structural and spectroscopic characterization, biological activity of five heteroligand copper(II) complexes with diethylnicotinamide various fenamates, as follows: flufenamate (fluf), niflumate (nifl), tolfenamate (tolf), clonixinate (clon), mefenamate (mef) N, N-diethylnicotinamide (dena). The composition: [Cu(fluf)2(dena)2(H2O)2] (1), [Cu(nifl)2(dena)2] (2),...
Two closely related binding modes have previously been proposed for the ATP-competitive benzimidazole class of checkpoint kinase 2 (CHK2) inhibitors; however, neither binding mode is entirely consistent with the reported SAR. Unconstrained rigid docking of benzimidazole ligands into representative CHK2 protein crystal structures reveals an alternative binding mode involving a water-mediated int...
Molecular modeling is a set of computational techniques for construction of 3D structure of a protein especially membrane bound proteins whose structures can not be elucidated using experimental techniques. These techniques has been applied in the study of membrane metalloproteases for comparing wild and mutated enzymes, docking inhibitors in the catalytic site and examination of binding pocket...
Local anesthetics (LAs) are known to bind Na+ channels in the closed, open, and inactivated states and reach their binding sites via extracellular and intracellular access pathways. Despite intensive studies, no atomic-scale theory is available to explain the diverse experimental data on the LA actions. Here we attempt to contribute to this theory by simulating access and binding of LAs in the ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید